Evidence map›Paper›PMID 29070461›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2017

[Rictor/mTORC2 regulates blood-testis barrier and spermatogenesis in mice].

He-Ling Dong, Hong-Yuan Wu, You Fu, Meng Dai, Xiao-Chun Bai, Hong Wang

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

He-Ling DongCollege of Sports Science, Jinan University, Guangzhou 510632, China. E-mail: dongyihe914@163.com.
Hong-Yuan Wu
You Fu
Meng Dai
Xiao-Chun Bai
Hong Wang
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of Rictor/mTORC2 in the formation of blood testis barrier (BTB), testicular development, and spermatogenesis.

methodsAmh Cre positive mice homozygous for rictor loxP with Sertoli cell specific deletion of rictor were obtained by cross breeding Amh Cre mice with rictor loxP mice. The histology of the reproductive organs, seminiferous tubules and epididymis of the transgenic mice was observed with HE staining. The cell subgroups of the germ cells in the seminiferous tubule were detected by flow cytometry with propidium iodide labeling. The expression levels of Ki 67 and separase were detected with immunofluorescence assay, and the expression levels of BTB associated proteins were detected with immunofluorescence and Western blotting.

resultsCompared with the control (Amh Cre

conclusionRictor in testicular Sertoli cells is essential for maintaining BTB integrity and function and ensuring normal spermatogenesis in mice.

Indexed as

SpermatogenesisAnimalsBlood-Testis BarrierMaleMechanistic Target of Rapamycin Complex 2MiceMice, TransgenicRapamycin-Insensitive Companion of mTOR ProteinSeminiferous EpitheliumSertoli CellsTestisMechanistic Target of Rapamycin Complex 2Rapamycin-Insensitive Companion of mTOR Proteinrictor protein, mouse

Identifiers

PMID29070461
PMCPMC6743948
OpenAlexW2997685158

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.