ArticleBMC pharmacology & toxicology2017
Prescription of potentially inappropriate medications among older people with intellectual disability: a register study.
Article in BMC pharmacology & toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Investigating pain-related medication use and contribution to polypharmacy in adults with intellectual disabilities: a systematic review.BMC medicine · 2024Pooled it
- Comorbidities in People With Intellectual Disability With and Without Schizophrenia and Schizophrenia Without Intellectual Disability: A Swedish Register Study (IDcare).Journal of intellectual disability research : JIDR · 2026Article
- Structured Medication Review and Shared Decision-Making in Patients with Mild Intellectual Disabilities Who Use Psychotropic Medication.Pharmacy (Basel, Switzerland) · 2026Article
- Anticholinergics, executive function, and cognitive/behavioral changes in Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Exploring Connections Between Living Situations and Antipsychotic Prescribing Practices for People With Intellectual Disabilities.Psychiatric research and clinical practice · 2025Article
- Good life in old age: Qualitative interviews about ageing with older adults with mild intellectual disability, prior to an educational intervention.Journal of intellectual disabilities : JOID · 2024Article
- Potential use of salivary TNF-α as a vaccine-induced pain biomarker in people with cerebral palsy and communication disorders.PloS one · 2024Article
- Ageing people with intellectual disabilities and the association between frailty factors and social care: A Swedish national register study.Journal of intellectual disabilities : JOID · 2022Article
- A study on prescriptions contributing to the risk of high anticholinergic burden in adults with intellectual disabilities: retrospective record linkage study.Annals of general psychiatry · 2022Article
- Psychotropic drugs intake in people aging with intellectual disability: Prevalence and predictors.Journal of applied research in intellectual disabilities : JARID · 2022Article
- Support staff liaising effectively with professionals for the rational use of psychotropics for behaviours that challenge in adults with intellectual disabilities: Findings from a co-design event.Frontiers in psychiatry · 2022Article
- Specific Behavioral Responses Rather Than Autonomic Responses Can Indicate and Quantify Acute Pain among Individuals with Intellectual and Developmental Disabilities.Brain sciences · 2021Article
- Health care utilisation among older people with Down syndrome compared to specific medical guidelines for health surveillance: a Swedish national register study.BMC health services research · 2020Article
- Factors influencing trends in opioid prescribing for older people: a scoping review.Primary health care research & development · 2020Article
- Prescription of pain medication among older cancer patients with and without an intellectual disability: a national register study.BMC cancer · 2019Article
- Pharmacotherapy for mood and anxiety disorders in older people with intellectual disability in comparison with the general population.BMC psychiatry · 2019Article
- Observational
- Medication use and potentially inappropriate prescribing in older adults with intellectual disabilities: a neglected area of research.Therapeutic advances in drug safety · 2018Review
- Signs in People with Intellectual Disabilities: Interviews with Managers and Staff on the Identification Process of Dementia.Healthcare (Basel, Switzerland) · 2018Article
- Pain and Pain Medication among Older People with Intellectual Disabilities in Comparison with the General Population.Healthcare (Basel, Switzerland) · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlder people have a greater disease burden and are more likely than younger to be prescribed medications. They are also more sensitive to adverse effects. With this in mind, a range of medications have been suggested inappropriate in this population. People with intellectual disability (ID) have a higher disease burden than the general population, putting them at even greater risk of prescription of such medications. The aim of this study was to describe prescription of potentially inappropriate medications among older people with ID in relation to prescriptions among their age peers in the general population.
methodsWe established an administrative cohort of people with ID (ID cohort; n = 7936), using a Swedish national register. A referent cohort from the general population (gPop) was matched one-to-one by sex and year of birth. Data regarding prescription of potentially inappropriate medications were collected from the Swedish prescribed drug register for the years 2006-2012.
resultsPeople with ID were more likely than the general population to be prescribed medications with anticholinergic effects, intermediate- or long-acting benzodiazepines, and antipsychotics at least once during the study period, and also had more number of years with prescription. Except for benzodiazepines, those in the ID cohort with at least one prescription had larger amounts prescribed than those in the gPop cohort. People in the ID cohort were less likely than the general population to be prescribed non-steroidal anti-inflammatory drugs (NSAIDs). Among those with at least one prescription of NSAIDs, those in the ID cohort had prescriptions during fewer years and in lower amounts than those in the gPop cohort.
conclusionsAlthough prescription of potentially inappropriate medications overall is more common among people with ID than in the general population, the opposite pattern is found for medications for pain management. This may be a result of pain being under-recognized and under-treated in this population. Thus, there is a need for training as well as increased knowledge and awareness among care and health care professionals regarding signs of adverse effects and the need of continuous evaluation of treatment in this vulnerable group.
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Registered trials
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