Evidence map›Paper›PMID 29069861›Full record

ArticleOncotarget2017

Higher N stage and serum ferritin, but lower serum albumin levels are associated with distant metastasis and poor survival in patients with nasopharyngeal carcinoma following intensity-modulated radiotherapy.

Xiaoqian Chen, Xianfeng Long, Zhongguo Liang, Hao Lei, Ling Li, Song Qu, Xiaodong Zhu

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
  5. A Nomogram Based on Circulating CD4Journal of inflammation research · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoqian ChenDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.
Xianfeng LongDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.
Zhongguo LiangDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.
Hao LeiDepartment of Radiation Oncology, Hubei Cancer Hospital, Wuhan 430079, China.
Ling LiDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.
Song QuDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.
Xiaodong ZhuDepartment of Radiation Oncology, Cancer Hospital of Guangxi Medical University, Nanning 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the potential risk factors for distant metastasis of nasopharyngeal carcinoma in Chinese patients following standard intensity-modulated radiotherapy and chemotherapy.

methodsThe potential risk factors for distant metastasis in 622 patients with newly-diagnosed primary nasopharyngeal carcinoma following standard radiotherapy and chemotherapy were evaluated retrospectively by stratification, univariate and multivariate analyses. The 5-year overall survival, distant metastasis-free survival, local recurrence-free survival and progression-free survival rates were determined.

resultsUnivariate and multivariate analyses indicated that N2-3 stage, serum ferritin > 300 μg/L and serum albumin < 42 g/L were independent risk factors for distant metastasis of nasopharyngeal carcinoma (

conclusionsCombination of higher N stage, serum ferritin and lower serum albumin levels may be valuable for predicting distant metastasis of nasopharyngeal carcinoma patients following standard intensity-modulated radiotherapy and chemotherapy.

Indexed as

distant metastasisintensity-modulated radiotherapynasopharyngeal carcinomaserum albuminserum ferritin

Identifiers

PMID29069861
PMCPMC5641204

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