Evidence map›Paper›PMID 29069719›Full record

ArticleOncotarget2017

MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa.

Selamawit Tadesse, Georgia Corner, Elena Dhima, Michele Houston, Chandan Guha, Leonard Augenlicht, Anna Velcich

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. The Power of MUC2 in Mucinous Adenocarcinomas.Pathobiology : journal of immunopathology, molecular and cellular biology · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Microbiome research reports · 2023
    Review
  14. Article
  15. [Protective Effects ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Selamawit TadesseDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Georgia CornerDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Elena DhimaDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Michele HoustonDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Chandan GuhaDepartment of Radiation Oncology, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Leonard AugenlichtDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Anna VelcichDepartment of Medicine, Albert Einstein College of Medicine/Albert Einstein Cancer Center, NY, USA.
Albert Einstein College of Medicine · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI THOMAS E ROHAN · 1985 to 2026
$111.2M
Age and Diet: Major interacting factors that drive sporadic intestinal cancerR01CA174432 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2014 to 2018
$3.3M
Nutritionally Driven Sporadic Intestinal Tumors: Impact on Stem CellsR01CA229216 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$2.4M
A Major Nutritional Effect on Intestinal Stem Cells and TumorsR01CA214625 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$1.6M
NCI NIH HHS P30 CA013330NCI NIH HHS R01 CA174432NCI NIH HHS R01 CA214625NCI NIH HHS R01 CA229216
6 · The paper itself

Abstract

The mucus layer in the intestine affects several aspects of intestinal biology, encompassing physical, chemical protection, immunomodulation and growth, thus contributing to homeostasis. Mice with genetic inactivation of the

Indexed as

inflammationmetabolismMUC2mucintumorigenesis

Identifiers

PMID29069719
PMCPMC5641062
OpenAlexW2605130544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.