Evidence map›Paper›PMID 29069562›Full record

ArticleThe New England journal of medicine2017

Dabigatran Reversal with Idarucizumab.

Charles V Pollack, Paul A Reilly, Jeffrey I Weitz

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06393868 (Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06393868 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism: Pilot Randomized Study (RADIANT Study)

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2024 to 2028Enrolled360ConditionsVenous Thromboembolism, Gastro Intestinal Bleeding, Blood ClotArmsOmeprazole 20 mg Oral Tablet, Placebo
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Anticoagulation and bleeding in the cancer patient.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  6. Observational
  7. Anticoagulation and Spine Surgery.Global spine journal · 2020
    Article
  8. Perioperative management of anticoagulant therapy.Innovative surgical sciences · 2019
    Review
  9. Reversal of Anticoagulants in Critical Care.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
    Article
  10. Review
  11. Review
  12. Anticoagulation Resumption After Intracerebral Hemorrhage.Current atherosclerosis reports · 2018
    Review
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Charles V PollackThomas Jefferson University, Philadelphia, PA charles.pollack@jefferson.edu
Paul A ReillyBoehringer Ingelheim, Ridgefield, CT
Jeffrey I WeitzMcMaster University, Hamilton, ON, Canada

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntithrombinsDabigatranAntibodies, Monoclonal, HumanizedHumansAntibodies, Monoclonal, HumanizedAntithrombinsDabigatranidarucizumab

Identifiers

PMID29069562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.