ReviewFEMS microbiology reviews2018
Environmental factors influencing the development and spread of antibiotic resistance.
Review in FEMS microbiology reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 401 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
401 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Iran's Escherichia coli AMR Landscape (2010-2025): A One Health Systematic Review and Meta-Analysis.MicrobiologyOpen · 2026Pooled it
- Magnitude of Health Care Associated Infections and its Clinical Predictors in Ethiopia: A Systematic Review and Meta-Analysis.Journal of epidemiology and global health · 2025Pooled it
- Prevalence of antibiotic resistance inFrontiers in veterinary science · 2024Pooled it
- Quantifying conjugation rates in clinical and environmental matrices: a systematic review to inform risk assessment.Frontiers in microbiomes · 2024Pooled it
- Metagenomic-driven predictive biosafety and contamination traceability in stem cell manufacturing: Translating outbreak genomics into regenerative medicine.Regenerative therapy · 2026Review
- Farm-adapted multicomponent bacteriophage preparation for environmental biocontrol in commercial dairy cattle housing: A One Health approach.Veterinary world · 2026Article
- Synthesis and In Vitro Biological Evaluation of Amphiphilic Derivatives of Carvacrol as Potent Antibacterial Agents.Antibiotics (Basel, Switzerland) · 2026Article
- An integrative computational and experimental evaluation of natural compounds with potential to target LuxS in Klebsiella pneumoniae.Archives of microbiology · 2026Article
- Global genomic surveillance ofmBio · 2026Article
- Farming practices exert selection pressures on the resistome of natural populations of house mice.Nature communications · 2026Article
- Building the Tools for Enhanced Waterway Surveillance: Prediction of Antimicrobial-ResistantJournal of the Royal Society of New Zealand · 2026Article
- Occurrence of Antimicrobial Resistance in Kocuria rhizophila Bacteria Isolated From Salmo munzuricus (Teleostei: Salmonidae) Samples in Natural Resources.MicrobiologyOpen · 2026Article
- Multidrug-resistance in backyard poultry and their link to management and biosecurity conditions in Eastern Spain.Poultry science · 2026Article
- Beyond Antibiotics: One Health Education for Tackling Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2026Review
- Broad synergistic effects of an AMP with multiple antibiotics against drug-resistant bacteria via multifaceted mechanisms.Science China. Life sciences · 2026Article
- The mobile resistome in the water-soil-air nexus: horizontal gene transfer and environmental dissemination of antimicrobial resistance genes.FEMS microbiology ecology · 2026Review
- Free-ranging hedgehogs as sentinels of environmental extended-spectrum β-lactamase-producing Enterobacterales.One health (Amsterdam, Netherlands) · 2026Article
- From clinics to sewers: leveraging environmental surveillance and whole genome sequencing to inform transmission of ESBL-Applied and environmental microbiology · 2026Article
- Antimicrobial Resistance in Veterinary Bacterial Pathogens: Resistance Patterns, Zoonotic Risks and One Health Implications.Pathogens (Basel, Switzerland) · 2026Review
- Primary caregivers' practices and perceptions on antibiotic use and resistance: a one health qualitative study in rural South India.BMJ open · 2026Article
341 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic resistance and its wider implications present us with a growing healthcare crisis. Recent research points to the environment as an important component for the transmission of resistant bacteria and in the emergence of resistant pathogens. However, a deeper understanding of the evolutionary and ecological processes that lead to clinical appearance of resistance genes is still lacking, as is knowledge of environmental dispersal barriers. This calls for better models of how resistance genes evolve, are mobilized, transferred and disseminated in the environment. Here, we attempt to define the ecological and evolutionary environmental factors that contribute to resistance development and transmission. Although mobilization of resistance genes likely occurs continuously, the great majority of such genetic events do not lead to the establishment of novel resistance factors in bacterial populations, unless there is a selection pressure for maintaining them or their fitness costs are negligible. To enable preventative measures it is therefore critical to investigate under what conditions and to what extent environmental selection for resistance takes place. In addition, understanding dispersal barriers is not only key to evaluate risks, but also to prevent resistant pathogens, as well as novel resistance genes, from reaching humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.