ArticleGenome biology and evolution2017
Legionella Becoming a Mutualist: Adaptive Processes Shaping the Genome of Symbiont in the Louse Polyplax serrata.
Article in Genome biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 71 citations in OpenAlex.
- Detection and Genetic Diversity of Heritable Bacterial Symbionts in Human Lice Based on 16S-rRNA Gene.Environmental microbiology reports · 2026Article
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- An obligate symbiont ofApplied and environmental microbiology · 2025Article
- Generalist vs. specialist strategy shapes microbiomes in blood feeding parasiteFrontiers in microbiology · 2025Article
- Fur microbiome as a putative source of symbiotic bacteria in sucking lice.Scientific reports · 2024Article
- Discovery of a novel symbiotic lineage associated with a hematophagous leech from the genusMicrobiology spectrum · 2024Article
- Host-bacteria interactions: ecological and evolutionary insights from ancient, professional endosymbionts.FEMS microbiology reviews · 2024Review
- Highly Resolved Genomes of Two Closely Related Lineages of the Rodent Louse Polyplax serrata with Different Host Specificities.Genome biology and evolution · 2024Article
- Microbiomes of Blood-Feeding Triatomines in the Context of Their Predatory Relatives and the Environment.Microbiology spectrum · 2023Article
- Supergroup F Wolbachia with extremely reduced genome: transition to obligate insect symbionts.Microbiome · 2023Article
- Genomic Approaches to Uncovering the Coevolutionary History of Parasitic Lice.Life (Basel, Switzerland) · 2022Review
- Ecological Contacts and Host Specificity Promote Replacement of Nutritional Endosymbionts in Ticks.Microbial ecology · 2022Article
- Host Adaptation in Legionellales Is 1.9 Ga, Coincident with Eukaryogenesis.Molecular biology and evolution · 2022Article
- Endosymbiotic bacteria of the boar louseFrontiers in microbiology · 2022Article
- Cryptic Genes for Interbacterial Antagonism DistinguishFrontiers in cellular and infection microbiology · 2022Article
- Development and validation of an LC-MS/MS method for determination of B vitamins and some its derivatives in whole blood.PloS one · 2022Article
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- A dual endosymbiosis supports nutritional adaptation to hematophagy in the invasive tickeLife · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legionellaceae are intracellular bacteria known as important human pathogens. In the environment, they are mainly found in biofilms associated with amoebas. In contrast to the gammaproteobacterial family Enterobacteriaceae, which established a broad spectrum of symbioses with many insect taxa, the only instance of legionella-like symbiont has been reported from lice of the genus Polyplax. Here, we sequenced the complete genome of this symbiont and compared its main characteristics to other Legionella species and insect symbionts. Based on rigorous multigene phylogenetic analyses, we confirm this bacterium as a member of the genus Legionella and propose the name Candidatus Legionella polyplacis, sp.n. We show that the genome of Ca. Legionella polyplacis underwent massive degeneration, including considerable size reduction (529.746 bp, 484 protein coding genes) and a severe decrease in GC content (23%). We identify several possible constraints underlying the evolution of this bacterium. On one hand, Ca. Legionella polyplacis and the louse symbionts Riesia and Puchtella experienced convergent evolution, perhaps due to adaptation to similar hosts. On the other hand, some metabolic differences are likely to reflect different phylogenetic positions of the symbionts and hence availability of particular metabolic function in the ancestor. This is exemplified by different arrangements of thiamine metabolism in Ca. Legionella polyplacis and Riesia. Finally, horizontal gene transfer is shown to play a significant role in the adaptive and diversification process. Particularly, we show that Ca. L. polyplacis horizontally acquired a complete biotin operon (bioADCHFB) that likely assisted this bacterium when becoming an obligate mutualist.
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