ArticleAnnals of botany2018
Holocentric chromosomes: from tolerance to fragmentation to colonization of the land.
Article in Annals of botany, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 48 citations in OpenAlex.
- Transgenerational chromosome repair in the asexual bdelloid rotiferScience advances · 2026Article
- Hybridization and Polyploidy Shaped the Evolutionary History of a Complex of Cryptic Species in European Woodrushes (Luzula sect. Luzula).Systematic biology · 2026Article
- Towards identification of a holocentromere marker in the lepidopteran model Spodoptera frugiperda.Chromosoma · 2025Article
- Centromere drive may propel the evolution of chromosome and genome size in plants.Annals of botany · 2024Article
- Chromosomal evolution in Cryptangieae Benth. (Cyperaceae): Evidence of holocentrism and pseudomonads.Protoplasma · 2024Article
- Disentangling Relationships among the Alpine Species ofPlants (Basel, Switzerland) · 2023Article
- Article
- Kinetic Activity of Chromosomes and Expression of Recombination Genes in Achiasmatic Meiosis ofInternational journal of molecular sciences · 2022Article
- A revised lower estimate of ozone columns during Earth's oxygenated history.Royal Society open science · 2022Article
- Centromere size scales with genome size across Eukaryotes.Scientific reports · 2021Article
- A simple model explains the cell cycle-dependent assembly of centromeric nucleosomes in holocentric species.Nucleic acids research · 2021Article
- Comparative analysis of chromosome numbers and sex chromosome systems in Paraneoptera (Insecta).Comparative cytogenetics · 2021Review
- Meiosis Progression and Recombination in Holocentric Plants: What Is Known?Frontiers in plant science · 2021Review
- Holocentric Chromosomes Probably Do Not Prevent Centromere Drive in Cyperaceae.Frontiers in plant science · 2021Article
- Article
- Endopolyploidy is a common response to UV-B stress in natural plant populations, but its magnitude may be affected by chromosome type.Annals of botany · 2020Article
- Super-Resolution Microscopy Reveals Diversity of Plant Centromere Architecture.International journal of molecular sciences · 2020Review
- Article
- Analysis of retrotransposon abundance, diversity and distribution in holocentric Eleocharis (Cyperaceae) genomes.Annals of botany · 2018Article
- Understanding eukaryotic chromosome segregation from a comparative biology perspective.Journal of cell science · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The dispersed occurrence of holocentric chromosomes across eukaryotes implies they are adaptive, but the conditions under which they confer an advantage over monocentric chromosomes remain unclear. Due to their extended kinetochore and the attachment of spindle microtubules along their entire length, holocentric chromosomes tolerate fragmentation; hence, they may be advantageous in times of exposure to factors that cause chromosomal fragmentation (clastogens). Scope: It is shown that holocentric organisms may, indeed, thrive better than monocentric organisms under clastogenic conditions and that such conditions of various duration and intensity have occurred many times throughout the history of Earth's biota. One of the most important clastogenic events in eukaryotic history, in which holocentric chromosomes may have played the key role, was the colonization of land by plants and animals half a billion years ago. In addition to arguments supporting the anticlastogenic hypothesis of holocentric chromosomes and a discussion of its evolutionary consequences, experiments and analyses are proposed to explore this hypothesis in more depth. Conclusions: It is argued that the tolerance to clastogens explains the origin of holocentric lineages and may also have far-reaching consequences for eukaryotic evolution in general as exemplified by the potential role of holocentric chromosomes in terrestrialization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.