Evidence map›Paper›PMID 29068991›Full record

Observational studyMedicine2017

The prescribing trend of oral antidiabetic agents for type 2 diabetes in Taiwan: An 8-year population-based study.

Wei-Min Chu, Hsin-En Ho, Kuang-Hua Huang, Yu-Tse Tsan, Yi-Sheng Liou, Yueh-Hsin Wang, Meng-Chih Lee, Yu-Ching Li

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Wei-Min ChuInstitute of Medicine, Chung Shan Medical University, Taichung Department of Family Medicine, Taichung Veterans General Hospital, Chiayi Branch, Chiayi School of Medicine, National Yang-Ming University, Taipei Department of Family Medicine, Taichung Armed Force General Hospital, Taichung School of Medicine, National Defense Medical Center, Taipei Department of Health Service Administration, College of Public Health, China Medical University Division of Occupational Medicine, Department of Emergency Medicine, Taichung Veterans General Hospital School of Medicine, Chung Shan Medical University, Taichung School of Public Health, National Defense Medical Center, Taipei Department of Family Medicine, Taichung Veterans General Hospital Department of Family Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung Institute of Population Sciences, National Health Research Institutes, Miaoli County College of Management, Chao-Yung University of Technology Department of Public Health, China Medical University, Taichung Department of Family Medicine, Yuan Rung Hospital, Yuanlin, Changhwa, Taiwan.
Hsin-En Ho
Kuang-Hua Huang
Yu-Tse Tsan
Yi-Sheng Liou
Yueh-Hsin Wang
Meng-Chih Lee
Yu-Ching Li
China Medical University · CNChina Medical University · TWChung Shan Medical University · TWNational Yang Ming Chiao Tung University · TWTaichung Armed Forces General Hospital · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to evaluate the prescription trend and pattern of oral antidiabetic (OAD) medications, which are extensively used worldwide for treating type 2 diabetes, in 2 age groups.In this population-based study, data obtained from the National Health Insurance Research Database, Taiwan, were analyzed to investigate the prescription trend of all types of OAD medications during 2005 to 2012. We used descriptive statistics to demonstrate the trend of prescription patterns stratified by age (aged 65 years and above or younger than 65).Sulfonylurea (SU) was once the most commonly used drug, but the proportion of its prescription had declined gradually (76.83% in 2005 to 63.70% in 2012). Consequently, biguanide (BG) became the most commonly used drug since 2010 (64.31% in 2005 to 74.41% in 2012). In addition, the prescriptions of thiazolidinedione decreased significantly (9.20% in 2005 to 2.86% in 2012), whereas the usage of DPP-4 inhibitor increased with time (3.73% in 2009 to 19.64% in 2012). The treatment choice of SU and α-glucosidase inhibitor (AGI) was higher in elderly patients compared with the younger population (SU: 62.70% in 2012, AGI: 12.78% in 2012). Two-drug combination therapies were the prevalent treatment choices for patients with type 2 diabetes (44.77% in 2012), particularly in the elderly group; however, ≥3 drug combination therapies increased gradually during the study period, particularly in the younger group.This descriptive study presents the change in the prescription of OAD medication for different age groups during 2005 to 2012.

Indexed as

Administration, OralAgedAge FactorsBiguanidesDiabetes Mellitus, Type 2Dipeptidyl-Peptidase IV InhibitorsDrug Therapy, CombinationGlycoside Hydrolase InhibitorsHumansHypoglycemic AgentsMiddle AgedPractice Patterns, Physicians'Sulfonylurea CompoundsTaiwanThiazolidinediones2,4-thiazolidinedioneBiguanidesDipeptidyl-Peptidase IV InhibitorsGlycoside Hydrolase InhibitorsHypoglycemic AgentsSulfonylurea CompoundsThiazolidinediones

Identifiers

PMID29068991
PMCPMC5671824
OpenAlexW2765830920

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.