Evidence map›Paper›PMID 29068841›Full record

ArticleEpidemiology (Cambridge, Mass.)2018

Outcome-related, Auxiliary Variable Sampling Designs for Longitudinal Binary Data.

Jonathan S Schildcrout, Enrique F Schisterman, Melinda C Aldrich, Paul J Rathouz

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. New Designs for New Epidemiology.Epidemiology (Cambridge, Mass.) · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jonathan S Schildcrout
Enrique F Schisterman
Melinda C Aldrich
Paul J Rathouz

Funding

Outcome Dependent Sampling Studies of Longitudinal Data: Design and AnalysisR01HL094786 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jonathan Scott Schildcrout · 2009 to 2026
$6.1M
Oxidative Stress, Hormones and Women s HealthZIAHD008762 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PERKINS, NEIL · 2009 to 2025
$3.1M
ROC Curve MethodologyZIAHD008761 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SCHISTERMAN, ENRIQUE F. · 2009 to 2021
$2.1M
APPLIED GENOMICS IN CARDIOPULMONARY DISEASEU01HL066583 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GARCIA, JOE G. N. · 2000 to 2004
$2.0M
Statistical Methods for Longitudinal StudiesR01HL072966 · NHLBI · UNIVERSITY OF WASHINGTON · PI HEAGERTY, PATRICK J · 2003 to 2014
$1.9M
Genome-Wide Associations Environmental Interactions in the Lung Health StudyU01HG004738 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI BARNES, KATHLEEN C · 2008 to 2009
$1.2M
Unraveling Genetic Determinants of Lung Cancer Risk in African AmericansK07CA172294 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALDRICH, MELINDA · 2013 to 2017
$801k
EARLY INTERVENTION/CHRONIC OBSTRUCTIVE PULMONARY DISEASEN01HR046002 · HR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CONNETT, JOHN E · 1985 to 1998
–
NCI NIH HHS K07 CA172294NHGRI NIH HHS U01 HG004738NHLBI NIH HHS N01 HR046002NHLBI NIH HHS R01 HL072966NHLBI NIH HHS R01 HL094786NHLBI NIH HHS U01 HL066583
6 · The paper itself

Abstract

backgroundEpidemiologists have long used case-control and related study designs to enhance variability of response and information available to estimate exposure-disease associations. Less has been done for longitudinal data.

methodsWe discuss an epidemiological study design and analysis approach for longitudinal binary response data. We seek to gain statistical efficiency by oversampling relatively informative subjects for inclusion into the sample. In this methodological demonstration, we develop this concept by sampling repeatedly from an existing cohort study to estimate the relationship of chronic obstructive pulmonary disease to past-year smoking in a panel of baseline smokers. To account for oversampling, we describe a sequential offsetted regressions approach for valid inferences in this setting.

resultsTargeted sampling can lead to increased statistical efficiency when combined with sequential offsetted regressions. Efficiency gains are degraded with increased prevalence of the disease response variable, with decreased association between the sampling variable and the response, and with other design and analysis parameters, providing guidance to those wishing to use these types of designs in the future.

conclusionsThese designs hold promise for efficient use of resources in longitudinal cohort studies.

Indexed as

AdultBronchodilator AgentsCohort StudiesEpidemiologic MethodsFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedPrevalenceProbabilityPulmonary Disease, Chronic ObstructiveSmokingSmoking CessationBronchodilator Agents

Identifiers

PMID29068841
PMCPMC5718926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.