Evidence map›Paper›PMID 29068688›Full record

ArticleOrganic letters2017

Direct, Mild, and General n-Bu

Makeda A Tekle-Smith, Kevin S Williamson, Isaac F Hughes, James L Leighton

Abstract read
In one paragraph

Article in Organic letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Makeda A Tekle-SmithDepartment of Chemistry, Columbia University , New York, New York 10027, United States.
Kevin S WilliamsonDepartment of Chemistry, Columbia University , New York, New York 10027, United States.
Isaac F HughesDepartment of Chemistry, Columbia University , New York, New York 10027, United States.
James L LeightonDepartment of Chemistry, Columbia University , New York, New York 10027, United States.ORCID 0000-0002-9061-8327

Funding

Asymmetric Synthesis of Marcolide AntibioticsR01GM058133 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI LEIGHTON, JAMES L · 1998 to 2017
$4.7M
NIGMS NIH HHS R01 GM058133
6 · The paper itself

Abstract

A direct, mild, and general method for the enantioselective allylsilylation of aldehydes with allyl chlorides is reported. The reactions are effectively catalyzed by 5 mol % of n-Bu

Indexed as

AldehydesAllyl CompoundsCatalysisMolecular StructureStereoisomerismAldehydesallyl chlorideAllyl Compounds

Identifiers

PMID29068688
PMCPMC5693333

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.