ArticleAnnals of the New York Academy of Sciences2017
Freezing does not alter multiscale tendon mechanics and damage mechanisms in tension.
Article in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Does the tendon retract in flexor hallucis longus muscle laceration? A cadaveric study.Archives of orthopaedic and trauma surgery · 2026Article
- Early adaptive and late degenerative tendon response to overload in rat model of synergist ablation.The Journal of physiology · 2025Article
- Fascicular Elastin Impacts Tendon-Specific Ramp-to-Failure and Fatigue Mechanics.Journal of biomechanical engineering · 2025Article
- Evaluating the impact of contrast agents on micro and nano mechanics of soft-to-hard tissue interface.Scientific reports · 2025Article
- Smaller Width Quadriceps Tendon Grafts Maintain Advantageous Biomechanical Properties for ACL Reconstruction.Orthopaedic journal of sports medicine · 2025Article
- Elevated fluid and glycosaminoglycan content in the Achilles tendon contribute to higher intratendinous pressures: Implications for Achilles tendinopathy.Journal of sport and health science · 2024Article
- Comparison of the Biomechanical Properties between Healthy and Whole Human and Porcine Stomachs.Bioengineering (Basel, Switzerland) · 2024Article
- Viscoelastic materials are most energy efficient when loaded and unloaded at equal rates.Journal of the Royal Society, Interface · 2024Article
- The alteration of the structure and macroscopic mechanical response of porcine patellar tendon by elastase digestion.Frontiers in bioengineering and biotechnology · 2024Article
- Guidelines for ex vivo mechanical testing of tendon.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Review
- A Strainer-Based Platform for the Collection and Immunolabeling of Mouse Intestinal Organoids.International journal of molecular sciences · 2023Article
- Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration.Journal of biomechanical engineering · 2023Article
- Approach to standardized material characterization of the human lumbopelvic system-Specification, preparation and storage.PloS one · 2023Article
- Stress deprivation of tendon explants or Tpm3.1 inhibition in tendon cells reduces F-actin to promote a tendinosis-like phenotype.Molecular biology of the cell · 2022Article
- Templated freezing: a simple method may increase gripping force of the clamp on the tendon.Journal of orthopaedic surgery and research · 2022Article
- Tendons exhibit greater resistance to tissue and molecular-level damage with increasing strain rate during cyclic fatigue.Acta biomaterialia · 2021Article
- Tear propagation in vaginal tissue under inflation.Acta biomaterialia · 2021Article
- Effect of storage and preconditioning of healing rat Achilles tendon on structural and mechanical properties.Scientific reports · 2021Article
- The influence of different sample preparation on mechanical properties of human iliotibial tract.Scientific reports · 2020Article
- Multi-Scale Loading and Damage Mechanisms of Plantaris and Rat Tail Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It is common in biomechanics to use previously frozen tissues, where it is assumed that the freeze-thaw process does not cause consequential mechanical or structural changes. We have recently quantified multiscale tendon mechanics and damage mechanisms using previously frozen tissue, where damage was defined as an irreversible change in the microstructure that alters the macroscopic mechanical parameters. Because freezing has been shown to alter tendon microstructures, the objective of this study was to determine if freezing alters tendon multiscale mechanics and damage mechanisms. Multiscale testing using a protocol that was designed to evaluate tendon damage (tensile stress-relaxation followed by unloaded recovery) was performed on fresh and previously frozen rat tail tendon fascicles. At both the fascicle and fibril levels, there was no difference between the fresh and frozen groups for any of the parameters, suggesting that there is no effect of freezing on tendon mechanics. After unloading, the microscale fibril strain fully recovered, and interfibrillar sliding only partially recovered, suggesting that the tendon damage is localized to the interfibrillar structures and that mechanisms of damage are the same in both fresh and previously frozen tendons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.