Evidence map›Paper›PMID 29068373›Full record

ArticleMolecules (Basel, Switzerland)2017

A Search for Dual Action HIV-1 Reverse Transcriptase, Bacterial RNA Polymerase Inhibitors.

Agata Paneth, Tomasz Frączek, Agnieszka Grzegorczyk, Dominika Janowska, Anna Malm, Piotr Paneth

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Agata PanethDepartment of Organic Chemistry, Medical University of Lublin, 20-093 Lublin, Poland. agata.paneth@umlub.pl.
Tomasz FrączekInstitute of Applied Radiation Chemistry, Lodz University of Technology, 90-924 Lodz, Poland. tomasz.fraczek@p.lodz.pl.
Agnieszka GrzegorczykDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 20-093 Lublin, Poland. agnieszka.grzegorczyk@umlub.pl.ORCID 0000-0002-2812-5046
Dominika JanowskaDepartment of Organic Chemistry, Medical University of Lublin, 20-093 Lublin, Poland. dominika.hagel@gmail.com.
Anna MalmDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 20-093 Lublin, Poland. anna.malm@umlub.pl.
Piotr PanethInstitute of Applied Radiation Chemistry, Lodz University of Technology, 90-924 Lodz, Poland. piotr.paneth@p.lodz.pl.ORCID 0000-0002-3091-8387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using molecular modeling approach, potential antibacterial agents with triazole core were proposed. A moderate to weak level of antibacterial activity in most of the compounds have been observed, with best minimal inhibitory concentration (MIC) value of 0.003 mg/mL, as shown by the

Indexed as

Anti-Bacterial AgentsAntifungal AgentsAnti-Retroviral AgentsBacterial ProteinsCandida albicansCandida parapsilosisDNA-Directed RNA PolymerasesEnzyme InhibitorsHIV Reverse TranscriptaseMicrobial Sensitivity TestsModels, MolecularMolecular Docking SimulationMolecular StructureStaphylococcus epidermidisStructure-Activity RelationshipTriazolesAnti-Bacterial AgentsAntifungal AgentsAnti-Retroviral AgentsBacterial ProteinsDNA-Directed RNA PolymerasesEnzyme InhibitorsHIV Reverse TranscriptaseTriazolesantibacterial activitymolecular modelingtriazoles

Identifiers

PMID29068373
PMCPMC6150362

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.