Evidence map›Paper›PMID 29068255›Full record

ArticleVascular medicine (London, England)2018

Burden of hospitalization in clinically diagnosed peripheral artery disease: A community-based study.

Adelaide M Arruda-Olson, Homam Moussa Pacha, Naveed Afzal, Sara Abram, Bradley R Lewis, Iyad Isseh, Raad Haddad, Christopher G Scott, Kent Bailey, Hongfang Liu and 2 more

Abstract read
In one paragraph

Article in Vascular medicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Geographic Disparities in Readmissions for Peripheral Artery Disease in South Carolina.International journal of environmental research and public health · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Adelaide M Arruda-Olson1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Homam Moussa Pacha1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Naveed Afzal2 Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
Sara Abram1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Bradley R Lewis1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Iyad Isseh1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Raad Haddad1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Christopher G Scott2 Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
Kent Bailey2 Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
Hongfang Liu2 Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
Thom W Rooke1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.
Iftikhar J Kullo1 Department of Cardiovascular Diseases, Mayo Clinic Rochester, Rochester, MN, USA.

Funding

Genomic Basis of Susceptibility to COVID-19 Infection and its ComplicationsU01HG006379 · NHGRI · MAYO CLINIC ROCHESTER · PI Richard R. Sharp · 2011 to 2026
$16.5M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
EMR Phenotypes and Community Engaged Genomic AssociationsU01HG004599 · NHGRI · MAYO CLINIC ROCHESTER · PI CHUTE, CHRISTOPHER G · 2007 to 2010
$3.7M
Novel Informatics Approaches for Ascertainment of PAD Status and Adverse OutcomesK01HL124045 · NHLBI · MAYO CLINIC ROCHESTER · PI ARRUDA-OLSON, ADELAIDE MARIA MARTINS · 2015 to 2019
$820k
NHGRI NIH HHS U01 HG004599NHGRI NIH HHS U01 HG006379NHLBI NIH HHS K01 HL124045NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

The burden and predictors of hospitalization over time in community-based patients with peripheral artery disease (PAD) have not been established. This study evaluates the frequency, reasons and predictors of hospitalization over time in community-based patients with PAD. We assembled an inception cohort of 1798 PAD cases from Olmsted County, MN, USA (mean age 71.2 years, 44% female) from 1 January 1998 through 31 December 2011 who were followed until 2014. Two age- and sex-matched controls ( n = 3596) were identified for each case. ICD-9 codes were used to ascertain the primary reasons for hospitalization. Patients were censored at death or last follow-up. The most frequent reasons for hospitalization were non-cardiovascular: 68% of 8706 hospitalizations in cases and 78% of 8005 hospitalizations in controls. A total of 1533 (85%) cases and 2286 (64%) controls ( p < 0.001) were hospitalized at least once; 1262 (70%) cases and 1588 (44%) controls ( p < 0.001) ≥ two times. In adjusted models, age, prior hospitalization and comorbid conditions were independently associated with increased risk of recurrent hospitalizations in both groups. In cases, severe PAD (ankle-brachial index < 0.5) (HR: 1.25; 95% CI: 1.15, 1.36) and poorly compressible arteries (HR: 1.26; 95% CI: 1.16, 1.38) were each associated with increased risk for recurrent hospitalization. We demonstrate an increased rate of hospitalization in community-based patients with PAD and identify predictors of recurrent hospitalizations. These observations may inform strategies to reduce the burden of hospitalization of PAD patients.

Indexed as

CardiologyAgedAged, 80 and overAnkle Brachial IndexFemaleFollow-Up StudiesHospitalizationHumansLength of StayMaleMiddle AgedMinnesotaPeripheral Arterial DiseaseRiskRisk Factorshospitalizationperipheral artery disease (PAD)vascular medicine

Identifiers

PMID29068255
PMCPMC5807167

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.