Evidence map›Paper›PMID 29067919›Full record

SynthesisJournal of postgraduate medicine

Smoking and risk of colonic diverticulosis: A meta-analysis.

K Wijarnpreecha, B Boonpheng, C Thongprayoon, V Jaruvongvanich, P Ungprasert

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of postgraduate medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The Epidemiology of Diverticulitis.Clinics in colon and rectal surgery · 2025
    Review
  3. Sex-Specific Multimorbidity-Multibehaviour Patterns in Primary Care Populations.International journal of environmental research and public health · 2025
    Observational
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

K WijarnpreechaDepartment of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.
B BoonphengDepartment of Internal Medicine, East Tennessee State University, Johnson City, TN, USA.
C ThongprayoonDepartment of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.
V JaruvongvanichDepartment of Internal Medicine, University of Hawaii, Honolulu, USA.
P UngprasertDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA; Department of Medicine, Division of Rheumatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Bassett Medical Center · USEast Tennessee State University · USMahidol University · THUniversity of Hawaii System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe possible relationship between smoking and risk of colonic diverticulosis has been suggested by recent epidemiological studies, although the results were inconsistent. This meta-analysis was conducted to summarize all available data.

methodsA comprehensive literature review was conducted using the MEDLINE and EMBASE databases through May 2017 to identify all studies that compared the risk of colonic diverticulosis among current and former smokers versus nonsmokers. Effect estimates from each study were extracted and combined together using the random-effect, generic inverse variance method of DerSimonian and Laird.

resultsOf 465 potentially eligible articles, three prospective cohort studies with 130,520 participants met the eligibility criteria and were included in the meta-analysis. The risk of colonic diverticulosis in current smokers was significantly higher than nonsmokers with the pooled risks ratio of 1.46 (95% confidence interval [CI], 1.13-1.89). However, the risk of colonic diverticulosis in former smokers was not significantly higher than nonsmokers with the pooled risk ratio of 1.13 (95% CI, 0.88-1.44).

conclusionsA significantly increased risk of colonic diverticulosis among current smokers is demonstrated in this study.

Indexed as

Diverticulosis, ColonicHumansRisk AssessmentRisk FactorsSmoking

Identifiers

PMID29067919
PMCPMC5820812
OpenAlexW2765722140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.