Evidence map›Paper›PMID 29067768›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2017

Comparative risk of new-onset diabetes mellitus for antihypertensive drugs: A network meta-analysis.

Zimeng Li, Yi Li, Yulong Liu, Wenbo Xu, Qing Wang

Abstract readNetwork Meta-Analysis
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Evidence-based blood tests for monitoring adults with hypertension in primary care: rapid review, routine data analyses, and consensus study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Japanese Clinical Practice Guideline for Diabetes 2019.Journal of diabetes investigation · 2020
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zimeng LiDepartment of Endocrinology, China-Japan Union Hospital of Jilin University, Changchun, China.
Yi LiDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun, China.
Yulong LiuDepartment of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Wenbo XuClinical Medical College of Jilin University, Changchun, China.
Qing WangDepartment of Endocrinology, China-Japan Union Hospital of Jilin University, Changchun, China.ORCID http://orcid.org/0000-0002-4985-3798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New-onset diabetes mellitus (NOD) refers to forms of diabetes mellitus that develop during the therapeutic processes of other diseases such as hypertension. This study has been conducted in a network meta-analysis to compare antihypertensive drugs by identifying both the advantages and disadvantages on NOD by focusing on their respective effect rates. Odd ratios and corresponding 95% confidence intervals or credible intervals were calculated within pairwise and network meta-analysis. A total of 38 articles with 224 140 patients were included to evaluate the preventive effect of hypertension drugs on NOD. From the network meta-analysis it was evident that both angiotensin-converting enzyme inhibitor as well as angiotensin receptor blocker treatments are associated with a lower risk of developing NOD compared with placebo, with ranking probabilities of 79.81% and 72.77%, respectively, while β-blockers and calcium channel blockers may significantly increase the probability of developing NOD (β-blockers: odds ratio, 2.18 [95% credible intervals: 1.36-3.50]; calcium channel blockers: odds ratio, 1.16 [95% credible intervals, 1.05-1.29]). In conclusion, angiotensin receptor blockers have an advantage over the other treatments regarding the NOD.

Indexed as

Antihypertensive AgentsDiabetes MellitusHumansHypertensionRisk AssessmentRisk FactorsAntihypertensive Agentshypertensionnetwork meta-analysisnew-onset diabetes mellitus

Identifiers

PMID29067768
PMCPMC8030754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.