Evidence map›Paper›PMID 29067610›Full record

ArticleEnvironmental science and pollution research international2018

Regulatory role of miR-18a to CCN2 by TGF-β1 signaling pathway in pulmonary injury induced by nano-SiO

Hong Yang, Wenchao Li, Yingjian Zhang, Mingyue Li, Ying Gao, Canshan Lao, Bing Shi

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hong YangKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China. yanghongr@seu.edu.cn.ORCID http://orcid.org/0000-0001-6740-3232
Wenchao LiKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Yingjian ZhangKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Mingyue LiKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Ying GaoKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Canshan LaoKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Bing ShiKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, People's Republic of China.
Southeast University · CN

Funding

the Major State Basic Research Development Program of China (973Program) 2011CB933404the National Natural Science Foundation of China 81273046the Preventive Medicine Research Projects of Jiangsu Province Y2012039
6 · The paper itself

Abstract

This research is designed to investigate the regulatory effect of miR-18a to the target gene connective tissue growth factor (CTGF, or CCN2), by participating in TGF-β1 signaling pathway and explore the pathogenic mechanism of miR-18a in pulmonary injury induced by nano-SiO

Indexed as

AnimalsCell LineConnective Tissue Growth FactorCricetinaeFibroblastsGene Expression RegulationLung InjuryMicroRNAsNanoparticlesRatsSignal TransductionSilicon DioxideTransforming Growth Factor beta1Connective Tissue Growth FactorMicroRNAsSilicon DioxideTransforming Growth Factor beta1CCN2miR-18aNano-SiO2Pulmonary injuryTGF-β1 signaling pathway

Identifiers

PMID29067610
OpenAlexW2766042821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.