Trial reportSurgical endoscopy2018
Transanal versus abdominal low rectal dissection for rectal cancer: long-term results of the Bordeaux' randomized trial.
Trial report in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0.Annals of coloproctology · 2026Guideline
- EAES, ESCP, and ESGAR update on taTME for rectal cancer-systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- Outcomes of transanal versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis and trial sequential analysis of matched cohort studies.Surgical endoscopy · 2025Pooled it
- Transanal versus transabdominal total mesorectal excision for rectal cancer in minimally invasive surgery: meta-analysis.BJS open · 2025Pooled it
- Long-term oncologic outcomes of transanal TME compared with transabdominal TME for rectal cancer: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Comparison of oncological and functional outcomes and quality of life after transanal or laparoscopic total mesorectal excision for rectal cancer: a systematic review and meta-analysis.Techniques in coloproctology · 2021Pooled it
- Impact of neoadjuvant treatment on functional outcomes after transanal total mesorectal excision (taTME)-a case series.Surgical endoscopy · 2025Trial
- Outcomes of open vs laparoscopic vs robotic vs transanal total mesorectal excision (TME) for rectal cancer: a network meta-analysis.Techniques in coloproctology · 2023Review
- Meta-analysis of transanalWorld journal of gastrointestinal surgery · 2022Article
- Transanal down-to-up dissection of the distal rectum as a viable approach to achieve total mesorectal excision in laparoscopic sphincter-preserving surgery for rectal cancer near the anus: a study of short- and long-term outcomes of 123 consecutive patients from a single Japanese institution.World journal of surgical oncology · 2022Article
- Transanal versus laparoscopic total mesorectal excision: a comparative study of long-term oncological outcomes.Techniques in coloproctology · 2022Article
- Transanal versus Laparoscopic Total Mesorectal Excision in Male Patients with Low Tumor Location after Neoadjuvant Therapy: A Propensity Score-Matched Cohort Study.Gastroenterology research and practice · 2022Article
- Clinical Robotic Surgery Association (India Chapter) and Indian rectal cancer expert group's practical consensus statements for surgical management of localized and locally advanced rectal cancer.Frontiers in oncology · 2022Article
- Transanal total mesorectal excision: the Slagelse experience 2013-2019.Surgical endoscopy · 2021Article
- Transanal total mesorectal excision: 3-year oncological outcomes.Techniques in coloproctology · 2021Article
- Role of minimally invasive surgery for rectal cancer.World journal of gastroenterology · 2020Review
- The ACPGBI recommends pause for reflection on transanal total mesorectal excision.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020Article
- What is the advantage of rectal amputation with an initial perineal approach for primary anorectal carcinoma?BMC surgery · 2020Article
- [Transanal total mesorectal excision-a critical appraisal].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019Review
- Oncological Outcomes and Quality of Life After Rectal Cancer Surgery.Open medicine (Warsaw, Poland) · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the current study is to report long-term outcomes after transanal low rectal dissection compared with the conventional laparoscopic approach within the context of the Bordeaux' randomized trial. Results from this randomized trial have indicated that transanal approach was more effective than laparoscopic dissection regarding the rate of negative circumferential resection margin (CRM). Despite a high number of publications regarding the transanal approach for TME, there were no long-term data on survival and local recurrence which are now required.
methodsOne hundred patients with low rectal cancer suitable for laparoscopic TME with handsewn coloanal anastomosis were randomized in transanal versus laparoscopic low rectal dissection from 2008 to 2012. The randomization ratio was 1:1. All patients included in the trial were considered for long-term assessment. Local recurrence, overall- and disease-free survival were assessed by Kaplan-Meier and compared with Log-rank test.
resultsThe follow up was 60.2 months, similar in both group (p = 0.321). Overall, there were no differences of long-term outcomes. There was a significant association between CRM involvement and local recurrence (p = 0.011), however, the 5-year local recurrence rate was 4%, without any significant difference between transanal and laparoscopic dissection: 3% vs. 5%; p = 0.300. The 5-year disease-free survival was 73%: 72% vs. 74; p = 0.351.
conclusionLower positivity of the circumferential resection margin was reported after transanal low rectal dissection, but it did not translate into a decreased incidence of local recurrence. Further investigations are necessary to demonstrate advantages of this new procedure.
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