Evidence map›Paper›PMID 29067540›Full record

ArticleJournal of behavioral medicine2018

Attachment and telomere length: more evidence for psychobiological connections between close relationships, health, and aging.

Kyle W Murdock, Samuele Zilioli, Khadija Ziauddin, Cobi J Heijnen, Christopher P Fagundes

Abstract read
In one paragraph

Article in Journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyle W MurdockDepartment of Psychology, Rice University, Houston, TX, USA. kyle.murdock@psu.edu.
Samuele ZilioliDepartment of Psychology, Wayne State University, Detroit, MI, USA.
Khadija ZiauddinDepartment of Psychology, Rice University, Houston, TX, USA.
Cobi J HeijnenDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Christopher P FagundesDepartment of Psychology, Rice University, Houston, TX, USA.

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
UNDERSTANDING SHARED PSYCHOBIOLOGICAL PATHWAYSP50HL065112 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN A · 1999 to 2003
$5.0M
Project Heart: Biobehavioral Effects on Cardiovascular Risk for Bereaved SpousesR01HL127260 · NHLBI · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2015 to 2019
$4.1M
UNDERSTANDING SHARED PSYCHOBIOLOGICAL PATHWAYSP50HL065111 · NHLBI · CARNEGIE-MELLON UNIVERSITY · PI SCHEIER, MICHAEL F · 1999 to 2003
$3.1M
Social and psychological risk for infectious illnessR01AI066367 · NIAID · CARNEGIE-MELLON UNIVERSITY · PI COHEN, SHELDON A · 2005 to 2010
$2.8M
Social Ties and Health: Aggregating Data from Five Viral-Challenge TrialsR01AT006694 · NCCIH · CARNEGIE-MELLON UNIVERSITY · PI COHEN, SHELDON A · 2011 to 2015
$1.5M
Stress, Cellular Aging and Susceptibility to Infectious DiseaseRC1AT005799 · NCCIH · CARNEGIE-MELLON UNIVERSITY · PI COHEN, SHELDON A · 2009 to 2010
$448k
The Brain-Heart Connection: How Inhibition Relates to Cardiovascular DiseaseF32HL131353 · NHLBI · RICE UNIVERSITY · PI MURDOCK, KYLE W · 2016 to 2017
$60k
NCCIH NIH HHS R01 AT006694NCCIH NIH HHS RC1AT005799NCRR NIH HHS UL1 RR024153NHLBI NIH HHS 1F32HL131353NHLBI NIH HHS F32 HL131353NHLBI NIH HHS P50 HL065111NHLBI NIH HHS P50 HL065112NHLBI NIH HHS R01 HL127260NIAID NIH HHS R01 AI066367NIH HHS UL1 RR024153NIH HHS UL1 RT000005
6 · The paper itself

Abstract

Individuals with a history of poor interpersonal relationships are more likely to demonstrate negative health outcomes than those who have had high quality relationships. We sought to evaluate how attachment orientations, stress-induced respiratory sinus arrhythmia (RSA), and self-reported stress were associated with length of telomeres measured from peripheral blood mononuclear cells. Participants (N = 213) completed self-report measures of attachment and stress. Measurement of RSA was conducted before and after a stressful task and a blood draw was completed for analysis of telomere length. Attachment orientations were not directly associated with telomere length; however, we found that high attachment anxiety was associated with shorter length of telomeres via high self-reported stress. Attachment avoidance was also associated with telomere length via self-reported stress, but only among those with high stress-induced RSA. Exploratory analyses of T cell subsets indicated that stress was most strongly associated with telomeres from CD8CD28+ cells in comparison to CD8CD28- and CD4 cells. Study findings indicate that attachment orientations are associated with telomere length via stress, providing novel insights into the mechanisms through which close relationships can impact health and aging.

Indexed as

Object AttachmentAdultAgingFemaleHumansLeukocytes, MononuclearMaleRespiratory Sinus ArrhythmiaSelf ReportStress, PsychologicalTelomere HomeostasisT-Lymphocyte SubsetsYoung AdultAttachment orientationsClose relationshipsRespiratory sinus arrhythmiaStressTelomere length

Identifiers

PMID29067540
PMCPMC5916749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.