Evidence map›Paper›PMID 29067331›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2017

Inferior parietal transcranial direct current stimulation with training improves cognition in anomic Alzheimer's disease and frontotemporal dementia.

Carlos Roncero, Heike Kniefel, Erik Service, Alexander Thiel, Stephan Probst, Howard Chertkow

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05386394 (Phase II Clinical Trial of Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia), which is not on this map. Cited by 62 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05386394 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Phase II Clinical Trial of Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

TypeinterventionalSponsorJohns Hopkins UniversityRan2024 to 2028Enrolled180ConditionsPrimary Progressive Aphasia, Logopenic Progressive Aphasia, Non-Fluent Primary Progressive AphasiaArmsActive tDCS + Language Therapy, Sham tDCS + Language Therapy
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos RonceroBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Heike KniefelBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Erik ServiceBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Alexander ThielBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Stephan ProbstBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Howard ChertkowBloomfield Centre for Research in Aging, Lady Davis Institute of Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe evaluated whether transcranial direct current stimulation (tDCS) can improve picture-naming abilities in subjects with anomic Alzheimer or frontotemporal dementias.

methodsUsing a double-blind crossover design, 10 participants were trained on picture naming over a series of 10 sessions with either 30 minutes of anodal (2 mA) tDCS stimulation to the left inferior parieto-temporal region (P3) or sham stimulation. We evaluated performance on a trained picture-naming list, an equivalent untrained list, and additional neuropsychological tasks.

resultsParticipants improved significantly more receiving real stimulation rather than sham stimulation (40% vs. 19%, DISCUSSION: tDCS stimulation has promise as a treatment for anomia in demented individuals and the effect can generalize to unstudied items as well as other cognitive abilities.

Indexed as

AnomiaObject namingPPAtDCSTraining

Identifiers

PMID29067331
PMCPMC5651421

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.