ArticleAlzheimer's & dementia (New York, N. Y.)2017
A composite measure of cognitive and functional progression in Alzheimer's disease: Design of the Capturing Changes in Cognition study.
Article in Alzheimer's & dementia (New York, N. Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 37 citations in OpenAlex.
- Concordance Between Subtest-Based and Domain Score-Based Determinations of Cognitive Impairment on the SNSB-II.Dementia and neurocognitive disorders · 2026Article
- The feasibility and factor structure of a multi-domain cognitive test battery in older Kenyan adults.NPJ dementia · 2026Article
- The Role of Oligodendrocytes in Neurodegenerative Diseases: Unwrapping the Layers.International journal of molecular sciences · 2025Review
- Predicting amyloid beta accumulation in cognitively unimpaired older adults: Cognitive assessments provide no additional utility beyond demographic and genetic factors.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Theta-gamma-coupling as predictor of working memory performance in young and elderly healthy people.Molecular brain · 2024Article
- Rethinking the detection and diagnosis of Alzheimer's disease: Outcomes of a European Brain Council project.Aging brain · 2023Review
- Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease.Journal of the International Neuropsychological Society : JINS · 2021Article
- Activities of Daily Living and Categorization Skills of Elderly with Cognitive Deficit: A Preliminary Study.Brain sciences · 2021Article
- New approaches to symptomatic treatments for Alzheimer's disease.Molecular neurodegeneration · 2021Review
- Dutch Brain Research Registry for study participant recruitment: Design and first results.Alzheimer's & dementia (New York, N. Y.) · 2021Article
- Measuring global functioning in older adults with cognitive impairments using the Rasch model.BMC geriatrics · 2020Article
- Decline in cognitively complex everyday activities accelerates along the Alzheimer's disease continuum.Alzheimer's research & therapy · 2020Article
- Modelling prognostic trajectories of cognitive decline due to Alzheimer's disease.NeuroImage. Clinical · 2020Article
- An Operational Definition of 'Abnormal Cognition' to Optimize the Prediction of Progression to Dementia: What Are Optimal Cut-Off Points for Univariate and Multivariate Normative Comparisons?Journal of Alzheimer's disease : JAD · 2020Article
- Commentary: Composite cognitive and functional measures for early stage Alzheimer's disease trials.Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
- Plasma Neurofilament Light: A Marker of Neurodegeneration in Mild Behavioral Impairment.Journal of Alzheimer's disease : JAD · 2020Article
- The Cognitive-Functional Composite is sensitive to clinical progression in early dementia: Longitudinal findings from the Catch-Cog study cohort.Alzheimer's & dementia (New York, N. Y.) · 2020Article
- Assessing cognition and daily function in early dementia using the cognitive-functional composite: findings from the Catch-Cog study cohort.Alzheimer's research & therapy · 2019Article
- FDA position statement "Early Alzheimer's disease: Developing drugs for treatment, Guidance for Industry".Alzheimer's & dementia (New York, N. Y.) · 2019Review
- Cognitive composite score association with Alzheimer's disease plaque and tangle pathology.Alzheimer's research & therapy · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCognitive testing in Alzheimer's disease (AD) is essential for establishing diagnosis, monitoring progression, and evaluating treatments. Assessments should ideally be brief, reliable, valid, and reflect clinically meaningful changes. There is a lack of instruments that meet all these criteria. In the Capturing Changes in Cognition (Catch-Cog) study, we seek to correct these deficiencies through the development and validation of a composite measure combining cognition and function: the cognitive-functional composite (CFC). We expect that the CFC is able to detect clinically relevant changes over time in early dementia stages of AD. METHODS/
designWe will include patients ( DISCUSSION: By performing an independent longitudinal construct validation, the Catch-Cog study of the novel CFC will contribute to the improvement of disease monitoring and treatment evaluation in early dementia stages of AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.