Evidence map›Paper›PMID 29067233›Full record

ArticleJournal of clinical & translational endocrinology2016

Effect of a macronutrient preload on blood glucose level and pregnancy outcome in gestational diabetes.

Li Li, Jing Xu, Wenyi Zhu, Rong Fan, Qian Bai, Chen Huang, Jun Liu, Zhen Li, Magnus Sederholm, Gunnar Norstedt and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical & translational endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Management of gestational diabetes mellitusWorld journal of diabetes · 2024
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Li LiDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Jing XuDepartment of Endocrinology, Xinqiao Hospital, Chongqing 400037, China.
Wenyi ZhuDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Rong FanDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Qian BaiDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Chen HuangDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Jun LiuDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Zhen LiDepartment of Obstetrics and Gynecology, Xinqiao Hospital, Chongqing 400037, China.
Magnus SederholmDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Gunnar NorstedtDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Jian WangDepartment of Nutrition, Xinqiao Hospital, Chongqing 400037, China.
Xinqiao Hospital · CNKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of a macro-nutrient preload (Inzone Vitality) on blood glucose levels and pregnancy outcomes of gestational diabetes. The preload method involves the ingestion of a smaller amount of a macronutrient composition half an hour before regular meals. The hypothesis was that preload treatment will reduce postprandial glycemia in gestational diabetes.

methodsSixty-six diagnosed cases of gestational diabetes were randomly selected from gynecology and obstetrics outpatient clinic at Xinqiao Hospital in Chongqing. The patients were divided into an intervention group (33 cases) and a control group (33 cases), according to odd-even numbers of the random cases. The intervention group was treated with a macro-nutrient preload given 0.5 h before regular meals and the control group was given a comparative treatment consisting of a milk powder with similar energy content. The two groups were studied until delivery and the measured parameters included fasting blood glucose (FBG), 2-hour postprandial blood glucose (2h-PBG), delivery mode and neonatal birth weight.

resultsThe two groups showed no differences in FBG or 2h-PBG before the nutritional intervention. FBG and 2h-PBG after intervention and before delivery were significantly lower in the intervention group, treated with the macro nutrient preload compared to the control group (

conclusionA macro-nutrient composition, used as a preload, is effective in controlling FBG and PBG of gestational diabetes.

Indexed as

Gestational diabetesNutrition therapyPostprandial blood glucosePreload

Identifiers

PMID29067233
PMCPMC5644440
OpenAlexW2407621495

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.