ReviewVeterinary medicine and science2016
An extended release local anaesthetic: potential for future use in veterinary surgical patients?
Review in Veterinary medicine and science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Efficacy of Adductor Canal Block on Medial Knee Pain in Patients with Knee Osteoarthritis: A Randomized Single-Blind Placebo-Controlled Study.International journal of environmental research and public health · 2022Trial
- Pharmacokinetics of a Single Subcutaneous Extended-Release Buprenorphine (Ethiqa XR) in Healthy Beagles.Journal of veterinary pharmacology and therapeutics · 2026Article
- Ultrasound-Guided Sciatic and Saphenous Nerve Blocks Enhance Perioperative Analgesia in Sheep Undergoing Experimental Orthopaedic Hindlimb Surgery.Veterinary sciences · 2026Article
- Erector Spinae Plane Block for Perioperative Analgesia in a Rabbit.Veterinary sciences · 2025Article
- Pre-Clinical Assessment of Bupivacaine-Loaded Poly(ester urea) Thin Films for Controlled Drug Release and Effective Pain Management After Surgery.Advanced healthcare materials · 2025Article
- Liposomal bupivacaine as one component of the postoperative management of limb amputations in cats: a retrospective study.Journal of feline medicine and surgery · 2025Article
- Pain Relief Interventions in Australian Livestock Husbandry: A Review of Animal Welfare and Pain Duration.Animals : an open access journal from MDPI · 2024Review
- A randomized, blinded, placebo-controlled, prospective clinical study to evaluate the effectiveness of a diluted liposomal-encapsulated bupivacaine suspension in dogs undergoing a ventral midline celiotomy.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Anaesthesia in Veterinary Oncology: The Effects of Surgery, Volatile and Intravenous Anaesthetics on the Immune System and Tumour Spread.Animals : an open access journal from MDPI · 2023Review
- Nociception in Chicken Embryos, Part I: Analysis of Cardiovascular Responses to a Mechanical Noxious Stimulus.Animals : an open access journal from MDPI · 2023Article
- Evaluation of the usage of incisional liposomal bupivacaine as a local anaesthetic for dogs undergoing limb amputation.Veterinary medicine and science · 2023Article
- The Outcomes of an Opioid-Free Anaesthetic Plan in Fourteen Dogs Undergoing Enucleation Using an Ultrasound-Guided Supra-Temporal Retrobulbar Block: A Retrospective Case Series.Animals : an open access journal from MDPI · 2023Article
- The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear (Animal welfare (South Mimms, England) · 2023Article
- Use of Transversus Abdominis Plane and Intercostal Blocks in Bitches Undergoing Laparoscopic Ovariectomy: A Randomized Controlled Trial.Veterinary sciences · 2022Article
- Pharmacokinetics and efficacy of a novel long-acting bupivacaine formulation for cornual nerve block in calves.Frontiers in veterinary science · 2022Article
- Lidocaine and bupivacaine as part of multimodal pain management in a C57BL/6J laparotomy mouse model.Scientific reports · 2021Article
- Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1).Veterinary medicine and science · 2020Review
- Preliminary Evaluation of Sustained-release Compared with Conventional Formulations of Meloxicam in Sheep (Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- The US Opioid Epidemic and Its Impact on US General Practice Veterinarians.Frontiers in veterinary science · 2019Article
- Defining local nerve blocks for feline distal pelvic limb surgery: a cadaveric study.Journal of feline medicine and surgery · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most effective means of preventing the transduction and transmission of acute and perioperative pain is through the use of local anaesthetics. However, local anaesthetics currently available have a relatively short duration of action. Although there are several tools available to treat perioperative pain in companion animals, overall, there is an unmet need for products that can be administered in the clinic, and provide pain relief for the crucial first few days following surgery in the home environment. Specifically, in relation to local anaesthetics, there is a clear unmet need for a long-acting local anaesthetic that can be added to the multimodal analgesic protocol to provide pain relief to patients in the home environment or during extended hospitalization. Bupivacaine liposomal injectable suspension recently became available for use in humans, and has proven efficacious and safe. This paper will review the use of local anaesthetics, particularly bupivacaine, in dogs and cats, and introduce a new formulation of prolonged release bupivacaine that is in development for dogs and cats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.