Evidence map›Paper›PMID 29066944›Full record

ReviewFrontiers in neuroscience2017

A Polymer Physics Investigation of the Architecture of the Murine Orthologue of the

Andrea M Chiariello, Andrea Esposito, Carlo Annunziatella, Simona Bianco, Luca Fiorillo, Antonella Prisco, Mario Nicodemi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Further Delineation of Duplications ofInternational journal of molecular sciences · 2022
    Review
  2. Article
  3. Review
  4. Models of polymer physics for the architecture of the cell nucleus.Wiley interdisciplinary reviews. Systems biology and medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Andrea M ChiarielloDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Andrea EspositoDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Carlo AnnunziatellaDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Simona BiancoDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Luca FiorilloDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Antonella PriscoInstitute of Genetics and Biophysics, Consiglio Nazionale Delle Ricerche (CNR), Naples, Italy.
Mario NicodemiDipartimento di Fisica, Università di Napoli Federico II, Naples, Italy.
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli · ITBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEInstitute of Genetics and Biophysics · ITUniversity of Naples Federico II · IT

Funding

San Diego Center for 4D Nucleome ResearchU54DK107977 · NIDDK · LUDWIG INSTITUTE FOR CANCER RES LTD · PI MURRE, CORNELIS, REN, BING · 2015 to 2019
$9.4M
NIDDK NIH HHS U54 DK107977
6 · The paper itself

Abstract

In the last decade, the developments of novel technologies, such as Hi-C or GAM methods, allowed to discover that chromosomes in the nucleus of mammalian cells have a complex spatial organization, encompassing the functional contacts between genes and regulators. In this work, we review recent progresses in chromosome modeling based on polymer physics to understand chromatin structure and folding mechanisms. As an example, we derive in mouse embryonic stem cells the full 3D structure of the

Indexed as

7q11.23 locuschromatincongenital diseaseNeurosciencepolymer physics

Identifiers

PMID29066944
PMCPMC5641313
OpenAlexW2762490979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.