Evidence map›Paper›PMID 29066919›Full record

ReviewJournal of asthma and allergy2017

Differentiating vocal cord dysfunction from asthma.

Andrew Fretzayas, Maria Moustaki, Ioanna Loukou, Konstantinos Douros

Open access · goldAbstract readReview
In one paragraph

Review in Journal of asthma and allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Current unmet needs and potential solutions to uncontrolled asthma.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  10. Review
  11. Review
  12. A 10-year-old girl with acute shortness of breath.Paediatrics & child health · 2021
    Article
  13. Impact of comorbid conditions on asthmatic adults and children.NPJ primary care respiratory medicine · 2020
    Review
  14. Review
  15. Review
  16. Current opinions for the management of asthma associated with ear, nose and throat comorbidities.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Andrew FretzayasThird Department of Pediatrics, Athens University Medical School, "Attikon" University Hospital, Haidari, Greece.
Maria MoustakiDepartment of Cystic Fibrosis, "Aghia Sofia", Children's Hospital, Athens, Greece.
Ioanna LoukouDepartment of Cystic Fibrosis, "Aghia Sofia", Children's Hospital, Athens, Greece.
Konstantinos DourosRespiratory Unit, Third Department of Pediatrics, Athens University Medical School, "Attikon" University Hospital, Haidari, Greece.
Iaso Children’s Hospital · GRAthens Medical Center · GRUniversity General Hospital Attikon · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vocal cord dysfunction (VCD)-associated symptoms are not rare in pediatric patients. Dyspnea, wheezing, stridor, chest pain or tightness and throat discomfort are the most commonly encountered symptoms. They may occur either at rest or more commonly during exercise in patients with VCD, as well as in asthmatic subjects. The phase of respiration (inspiration rather than expiration), the location of the wheezing origin, the rapid resolution of symptoms, and the timing occurring in relation to exercise, when VCD is exercise induced, raise the suspicion of VCD in patients who may have been characterized as merely asthmatics and, most importantly, had not responded to the appropriate treatment. The gold standard method for the diagnosis of VCD is fiberoptic laryngoscopy, which may also identify concomitant laryngeal abnormalities other than VCD. However, as VCD is an intermittent phenomenon, the procedure should be performed while the patient is symptomatic. For this reason, challenges that induce VCD symptoms should be performed, such as exercise tests. Recently, for the evaluation of patients with exercise-induced VCD, continuous laryngoscopy during exercise (such as treadmill, bicycle ergometer, swimming) was used. A definite diagnosis of VCD is of importance, especially for those patients who have been erroneously characterized as asthmatics, without adequate response to treatment. In these cases, another therapeutic approach is necessary, which will depend on whether they suffer solely from VCD or from both conditions.

Indexed as

asthmachildrenCLEcontinuous laryngoscopy exercise testILOinducible laryngeal obstructionlaryngoscopyvocal cord dysfunction

Identifiers

PMID29066919
PMCPMC5644529
OpenAlexW2761087579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.