Evidence map›Paper›PMID 29066841›Full record

Observational studyScientific reports2017

Nomogram for Predicting Cardiovascular Mortality in Incident Peritoneal Dialysis Patients: An Observational Study.

Xi Xia, Chen Zhao, Qimei Luo, Qian Zhou, Zhenchuan Lin, Xiaobo Guo, Xueqin Wang, Jianxiong Lin, Xiao Yang, Xueqing Yu and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xi XiaThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Chen ZhaoThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Qimei LuoThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Qian ZhouThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Zhenchuan LinThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Xiaobo GuoSchool of Mathematics & Computational Science, Sun Yat-sen University, Department of Statistical Science, Guangzhou, 510275, People's Republic of China.
Xueqin WangSchool of Mathematics & Computational Science, Sun Yat-sen University, Department of Statistical Science, Guangzhou, 510275, People's Republic of China.
Jianxiong LinThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Xiao YangThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Xueqing YuThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China.
Fengxian HuangThe First Affiliated Hospital of Sun Yat-sen University, Department of Nephrology, Guangzhou, 510080, People's Republic of China. hfxyl@163.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular mortality risk is high for peritoneal dialysis (PD) patients but it varies considerably among individuals. There is no clinical tool to predict cardiovascular mortality for PD patients yet. Therefore, we developed a cardiovascular mortality risk nomogram in a PD patient cohort. We derived and internally validated the nomogram in incident adult PD patients randomly assigned to a training (N = 918) or a validation (N = 460) dataset. The nomogram was built using the LASSO Cox regression model. Increasing age, history of cardiovascular disease or diabetes were consistent predictors of cardiovascular mortality. Low hemoglobin and serum albumin, high hypersensitive C-reactive protein and decreasing 24 hours urine output were identified as non-traditional cardiovascular risk predictors. In the validation dataset, the above nomogram performed good discrimination (1 year c-statistic = 0.83; 3 year c-statistic = 0.78) and calibration. This tool can classify patients between those at high risk of cardiovascular mortality (high-risk group) and those of low risk (low-risk group). Cardiovascular mortality was significantly different in the internal validation set of patients for the high-risk group compared to the low-risk group (HR 3.77, 2.14-6.64; p < 0.001). This novel nomogram can accurately predict cardiovascular mortality risk in incident PD patients.

Indexed as

NomogramsPeritoneal DialysisAdultAgedCardiovascular DiseasesFemaleHumansLife StyleMaleMiddle AgedRisk AssessmentTreatment Outcome

Identifiers

PMID29066841
PMCPMC5654762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.