Evidence map›Paper›PMID 29066805›Full record

ArticleScientific reports2017

Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases.

Karl-Heinz Tomaszowski, Nadja Hellmann, Viviane Ponath, Hiroyuki Takatsu, Hye-Won Shin, Bernd Kaina

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. The Role of OPathology oncology research : POR · 2020
    Pooled it
  2. Direct targeting of GLUT1 in cancer: A decade of inhibitor discovery and medicinal chemistry insights.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  3. Review
  4. Metabolic heterogeneity in early-stage lung adenocarcinoma revealed by RNA-seq and scRNA-seq.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. OFrontiers in oncology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Karl-Heinz TomaszowskiDepartment of Toxicology, University Medical Center, Obere Zahlbacher Strasse 67, D-55131, Mainz, Germany.
Nadja HellmannInstitute for Molecular Biophysics, Johannes Gutenberg-University, Jakob Welder Weg 26, D-55128, Mainz, Germany.
Viviane PonathDepartment of Toxicology, University Medical Center, Obere Zahlbacher Strasse 67, D-55131, Mainz, Germany.
Hiroyuki TakatsuGraduate School of Pharmaceutical Sciences, and, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.
Hye-Won ShinGraduate School of Pharmaceutical Sciences, and, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.ORCID 0000-0002-9138-9554
Bernd KainaDepartment of Toxicology, University Medical Center, Obere Zahlbacher Strasse 67, D-55131, Mainz, Germany. kaina@uni-mainz.de.
Johannes Gutenberg University Mainz · DEKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The DNA repair protein O

Indexed as

Adenosine TriphosphatasesBiological TransportCell Line, TumorCell MembraneDNA Modification MethylasesDNA Repair EnzymesEnzyme InhibitorsGlucoseGlucose Transport Proteins, FacilitativeHumansTumor Suppressor ProteinsAdenosine TriphosphatasesDNA Modification MethylasesDNA Repair EnzymesEnzyme InhibitorsGlucoseGlucose Transport Proteins, FacilitativeMGMT protein, humanTumor Suppressor Proteins

Identifiers

PMID29066805
PMCPMC5655675
OpenAlexW2766093846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.