ArticleScientific reports2017
Complex furrows in a 2D epithelial sheet code the 3D structure of a beetle horn.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Morphogenesis of the carapace from phyllosoma to puerulus in the Japanese spiny lobster.Zoological letters · 2026Article
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- Unveiling the cell dynamics during the final shape formation of the tarsus in Drosophila adult leg by live imaging.Development genes and evolution · 2024Article
- Growth regulation bringing modularity to morphogenesis of complex three-dimensional exoskeletons.Proceedings. Biological sciences · 2024Article
- Morphological Observation of the Pupal Body of Trypoxylus dichotomus Using 9.4T MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Article
- Correlative microscopy and block-face imaging (CoMBI): a 3D imaging method with wide applicability in the field of biological science.Anatomical science international · 2023Review
- The draft genome sequence of the Japanese rhinoceros beetle Trypoxylus dichotomus septentrionalis towards an understanding of horn formation.Scientific reports · 2023Article
- Appearance of a transparent protrusion containing two pairs of legs on the apodous ring preceding the anamorphic molt in a millipede, Niponia nodulosa.Frontiers in zoology · 2023Article
- Impact of environmental asymmetry on epithelial morphogenesis.Scientific reports · 2022Article
- Correlative microscopy and block-face imaging (CoMBI) method for both paraffin-embedded and frozen specimens.Scientific reports · 2021Article
- Computational analyses decipher the primordial folding coding the 3D structure of the beetle horn.Scientific reports · 2021Article
- Genetical control of 2D pattern and depth of the primordial furrow that prefigures 3D shape of the rhinoceros beetle horn.Scientific reports · 2020Article
- Epithelial tissue folding pattern in confined geometry.Biomechanics and modeling in mechanobiology · 2020Article
- Structure and development of the complex helmet of treehoppers (Insecta: Hemiptera: Membracidae).Zoological letters · 2020Article
- Theoretical models for branch formation in plants.Journal of plant research · 2019Review
- Precise staging of beetle horn formation in Trypoxylus dichotomus reveals the pleiotropic roles of doublesex depending on the spatiotemporal developmental contexts.PLoS genetics · 2019Article
- Rhinoceros beetle horn development reveals deep parallels with dung beetles.PLoS genetics · 2018Article
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9 authors.
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Abstract
The external organs of holometabolous insects are generated through two consecutive processes: the development of imaginal primordia and their subsequent transformation into the adult structures. During the latter process, many different phenomena at the cellular level (e.g. cell shape changes, cell migration, folding and unfolding of epithelial sheets) contribute to the drastic changes observed in size and shape. Because of this complexity, the logic behind the formation of the 3D structure of adult external organs remains largely unknown. In this report, we investigated the metamorphosis of the horn in the Japanese rhinoceros beetle Trypoxylus dichotomus. The horn primordia is essentially a 2D epithelial cell sheet with dense furrows. We experimentally unfolded these furrows using three different methods and found that the furrow pattern solely determines the 3D horn structure, indicating that horn formation in beetles occurs by two distinct processes: formation of the furrows and subsequently unfolding them. We postulate that this developmental simplicity offers an inherent advantage to understanding the principles that guide 3D morphogenesis in insects.
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