ArticleScientific reports2017
A quantitative model of the phytochrome-PIF light signalling initiating chloroplast development.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Guard cell signal transduction mechanisms controlling stomatal movements by light, abscisic acid, CO2, VPD and heat.Plant physiology · 2026Review
- Retrograde signals control dynamic changes to the chromatin state at photosynthesis-associated loci.Nature communications · 2025Article
- Specific binding between Arabidopsis thaliana phytochrome-interacting factor 3 (AtPIF3) bHLH and G-box originated prior to embryophyte emergence.BMC plant biology · 2024Article
- Anterograde signaling controls plastid transcription via sigma factors separately from nuclear photosynthesis genes.Nature communications · 2022Article
- Coordination of Chloroplast Activity with Plant Growth: Clues Point to TOR.Plants (Basel, Switzerland) · 2022Article
- Systematic analysis of photo/sko-regulated germination and post-germination development of shallow photodormant seeds inFrontiers in plant science · 2022Article
- Red Light Optogenetics in Neuroscience.Frontiers in cellular neuroscience · 2021Review
- Beyond the limits of photoperception: constitutively active PHYTOCHROME B2 overexpression as a means of improving fruit nutritional quality in tomato.Plant biotechnology journal · 2020Article
- Phytochrome-Dependent Temperature Perception Modulates Isoprenoid Metabolism.Plant physiology · 2020Article
- Regulation of Photomorphogenic Development by Plant Phytochromes.International journal of molecular sciences · 2019Review
- Retrograde Signals Navigate the Path to Chloroplast Development.Plant physiology · 2018Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The components required for photosynthesis are encoded in two separate genomes, the nuclear and the plastid. To address how synchronization of the two genomes involved can be attained in early light-signalling during chloroplast development we have formulated and experimentally tested a mathematical model simulating light sensing and the following signalling response. The model includes phytochrome B (PhyB), the phytochrome interacting factor 3 (PIF3) and putative regulatory targets of PIF3. Closed expressions of the phyB and PIF3 concentrations after light exposure are derived, which capture the relevant timescales in the response of genes regulated by PIF3. Sequence analysis demonstrated that the promoters of the nuclear genes encoding sigma factors (SIGs) and polymerase-associated proteins (PAPs) required for expression of plastid encoded genes, contain the cis-elements for binding of PIF3. The model suggests a direct link between light inputs via PhyB-PIF3 to the plastid transcription machinery and control over the expression of photosynthesis components both in the nucleus and in the plastids. Using a pluripotent Arabidopsis cell culture in which chloroplasts develop from undifferentiated proplastids following exposure to light, we could experimentally verify that the expression of SIGs and PAPs in response to light follow the calculated expression of a PhyB-PIF3 regulated gene.
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