Evidence map›Paper›PMID 29066596›Full record

ArticlePhysiological reports2017

Abundance, localization, and functional correlates of the advanced glycation end-product carboxymethyl lysine in human myocardium.

Martin M LeWinter, Douglas Taatjes, Takamaru Ashikaga, Bradley Palmer, Nicole Bishop, Peter VanBuren, Stephen Bell, Cameron Donaldson, Markus Meyer, Kenneth B Margulies and 3 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Review
  8. The Diabetic Cardiorenal Nexus.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Martin M LeWinterCardiology Unit University of Vermont College of Medicine, Burlington, Vermont martin.lewinter@UVMHealth.org.
Douglas TaatjesCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Takamaru AshikagaCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Bradley PalmerCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Nicole BishopCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Peter VanBurenCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Stephen BellCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Cameron DonaldsonCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Markus MeyerCardiology Unit University of Vermont College of Medicine, Burlington, Vermont.
Kenneth B MarguliesNHLBI Heart Failure Research Network, Bethesda, Maryland.
Margaret RedfieldNHLBI Heart Failure Research Network, Bethesda, Maryland.
David A BullNHLBI Heart Failure Research Network, Bethesda, Maryland.
Michael ZileCardiology Division, Medical University of South Carolina, Charleston, South Carolina.
University of Vermont · USNational Heart Lung and Blood Institute · USMedical University of South Carolina · US

Funding

Sarcolemmal Calcium Extrusion Defect in Patients with Diastolic DysfunctionR01HL122744 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LUSTGARTEN, DANIEL L, MEYER, MARKUS · 2015 to 2019
$1.9M
NHLBI NIH HHS R01 HL122744
6 · The paper itself

Abstract

Advanced glycation end-products (AGEs) play a role in the pathophysiology of diabetes mellitus (DM) and possibly hypertension (HTN). In

Indexed as

AgedCase-Control StudiesCollagenCoronary DiseaseFemaleGlycation End Products, AdvancedHeart VentriclesHumansLysineMaleMiddle AgedMyocardial ContractionMyocytes, CardiacVentricular FunctionCollagenGlycation End Products, AdvancedLysineN(6)-carboxymethyllysineAdvanced glycation end‐productscarboxymethyl lysinediabetes mellitushypertensionmyocardium

Identifiers

PMID29066596
PMCPMC5661230
OpenAlexW2765733673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.