Evidence map›Paper›PMID 29066580›Full record

ArticlePediatrics2017

Intelligence and Academic Achievement With Asymptomatic Congenital Cytomegalovirus Infection.

Adriana S Lopez, Tatiana M Lanzieri, Angelika H Claussen, Sherry S Vinson, Marie R Turcich, Isabella R Iovino, Robert G Voigt, A Chantal Caviness, Jerry A Miller, W Daniel Williamson and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Risk factors associated with late-onset hearing loss in children with congenital cytomegalovirus: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  8. Cytomegalovirus urinary excretion in children with congenital and postnatally acquired infection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Adriana S LopezNational Center for Immunization and Respiratory Diseases, and.
Tatiana M LanzieriNational Center for Immunization and Respiratory Diseases, and tmlanzieri@cdc.gov.
Angelika H ClaussenNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.
Sherry S VinsonTexas Children's Hospital, Houston, Texas.
Marie R TurcichTexas Children's Hospital, Houston, Texas.
Isabella R IovinoTexas Children's Hospital, Houston, Texas.
Robert G VoigtTexas Children's Hospital, Houston, Texas.
A Chantal CavinessTexas Children's Hospital, Houston, Texas.
Jerry A MillerTexas Children's Hospital, Houston, Texas.
W Daniel WilliamsonTexas Children's Hospital, Houston, Texas.
Craig M HalesNational Center for Immunization and Respiratory Diseases, and.
Stephanie R BialekNational Center for Immunization and Respiratory Diseases, and.
Gail Demmler-HarrisonTexas Children's Hospital, Houston, Texas.
Congenital Cytomegalovirus Longitudinal Study Group
Texas Children's Hospital · USNational Center for Immunization and Respiratory Diseases · USBaylor College of Medicine · USNational Center on Birth Defects and Developmental Disabilities · US

Funding

ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI PLON, SHARON E. · 1985 to 2011
$30.6M
UNDERSTANDING FXTAS AMONG MALES WITH THE FMR1 PREMUTATIONP30HD024064 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI ROSENMUND, CHRISTIAN · 1988 to 2013
$29.4M
Intramural CDC HHS CC999999NCRR NIH HHS M01 RR000188NICHD NIH HHS P30 HD024064
6 · The paper itself

Abstract

objectivesTo examine intelligence, language, and academic achievement through 18 years of age among children with congenital cytomegalovirus infection identified through hospital-based newborn screening who were asymptomatic at birth compared with uninfected infants.

methodsWe used growth curve modeling to analyze trends in IQ (full-scale, verbal, and nonverbal intelligence), receptive and expressive vocabulary, and academic achievement in math and reading. Separate models were fit for each outcome, modeling the change in overall scores with increasing age for patients with normal hearing (

resultsPatients with SNHL had full-scale intelligence and receptive vocabulary scores that were 7.0 and 13.1 points lower, respectively, compared with controls, but no significant differences were noted in these scores among patients with normal hearing and controls. No significant differences were noted in scores for verbal and nonverbal intelligence, expressive vocabulary, and academic achievement in math and reading among patients with normal hearing or with SNHL and controls.

conclusionsInfants with asymptomatic congenital cytomegalovirus infection identified through newborn screening with normal hearing by age 2 years do not appear to have differences in IQ, vocabulary or academic achievement scores during childhood, or adolescence compared with uninfected children.

Indexed as

Educational StatusIntelligenceIntelligence TestsAdolescentAdultAsymptomatic DiseasesChildChild, PreschoolCytomegalovirus InfectionsFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID29066580
PMCPMC5654402
OpenAlexW2765916645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.