Evidence map›Paper›PMID 29066545›Full record

ArticlemBio2017

Tuning of the Lethal Response to Multiple Stressors with a Single-Site Mutation during Clinical Infection by

Krishan Kumar, John Chen, Karl Drlica, Bo Shopsin

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Microbiota and metabolic adaptation shapebioRxiv : the preprint server for biology · 2024
    Article
  4. Quorum-sensingeLife · 2024
    Article
  5. Quorum-sensingbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Toxins · 2021
    Review
  10. Oxidative stress drives the selection of quorum sensing mutants in theProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  11. Article
  12. Review
  13. Genome Plasticity ofInfection and immunity · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Krishan KumarDepartments of Medicine and Microbiology, New York University School of Medicine, New York, New York, USA.
John ChenDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Karl DrlicaPublic Health Research Institute and Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA.
Bo ShopsinDepartments of Medicine and Microbiology, New York University School of Medicine, New York, New York, USA bo.shopsin@med.nyu.edu.
New York University · USNational University of Singapore · SGRutgers Health

Funding

Role of precipitous virulence in invasiveness of community-acquired methicillin-rR01AI103268 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, TORRES, VICTOR J. · 2013 to 2017
$2.1M
NIAID NIH HHS HHSN272201400019CNIAID NIH HHS R01 AI103268
6 · The paper itself

Abstract

The

Indexed as

MutationAnti-Bacterial AgentsBacterial ProteinsCiprofloxacinCross InfectionDaptomycinGene Expression Regulation, BacterialGenome, BacterialHumansQuorum SensingStaphylococcal InfectionsStaphylococcus aureusStress, PhysiologicalTrans-ActivatorsVirulenceAnti-Bacterial AgentsBacterial ProteinsCiprofloxacinDaptomycinTrans-ActivatorsagrAntibioticsciprofloxacindaptomycingentamicinresistanceStaphylococcus aureustolerance

Identifiers

PMID29066545
PMCPMC5654930
OpenAlexW2766247437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.