Evidence map›Paper›PMID 29066446›Full record

Observational studyJournal of the American Heart Association2017

Benefit of Vasodilating β-Blockers in Patients With Acute Myocardial Infarction After Percutaneous Coronary Intervention: Nationwide Multicenter Cohort Study.

Jaehoon Chung, Jung-Kyu Han, Young Jo Kim, Chong Jin Kim, Youngkeun Ahn, Myeong Chan Cho, Shung Chull Chae, In-Ho Chae, Jei Keon Chae, In-Whan Seong and 7 more

Open access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. β-Blocker Therapy After Myocardial Infarction: A Little Goes a Long Way.Journal of the American Heart Association · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Jaehoon ChungCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Jung-Kyu HanCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Young Jo KimDepartment of Internal Medicine, Yeungnam University Hospital, Daegu, Korea.
Chong Jin KimDepartment of Internal Medicine, Kyunghee University Hospital, Seoul, Korea.
Youngkeun AhnDepartment of Internal Medicine, Chonnam National University Hospital, Kwangju, Korea.
Myeong Chan ChoDepartment of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
Shung Chull ChaeDepartment of Internal Medicine, Kyungpook National University Hosptial, Daegu, Korea.
In-Ho ChaeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, Korea.
Jei Keon ChaeDepartment of Cardiovascular Medicine, Medical School of Chonbuk National University, Jeonju, Korea.
In-Whan SeongDepartment of Cardiology in Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.
Han-Mo YangCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Kyung-Woo ParkCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Hyun-Jae KangCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Bon-Kwon KooCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Myung Ho JeongDepartment of Internal Medicine, Chonnam National University Hospital, Kwangju, Korea.
Hyo-Soo KimCardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea hyosoo@snu.ac.kr.
investigators for Korea Acute Myocardial Infarction Registry (KAMIR)
Seoul National University Hospital · KRChonnam National University Hospital · KRJeonbuk National University · KRChungbuk National University Hospital · KRChungnam National University Hospital · KRKyungpook National University · KRSeoul National University Bundang Hospital · KRYeungnam University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough current guidelines recommend β-blocker after acute myocardial infarction (MI), the role of β-blocker has not been well investigated in the modern reperfusion era. In particular, the benefit of vasodilating β-blocker over conventional β-blocker is still unexplored. METHODS AND

resultsUsing nation-wide multicenter Korean Acute Myocardial Infarction Registry data, we analyzed clinical outcomes of 7127 patients with acute MI who underwent successful percutaneous coronary intervention with stents and took β-blockers: vasodilating β-blocker (n=3482), and conventional β-blocker (n=3645). In the whole population, incidence of cardiac death at 1 year was significantly lower in the vasodilating β-blocker group (vasodilating β-blockers versus conventional β-blockers, 1.0% versus 1.9%;

conclusionsVasodilating β-blocker therapy resulted in better clinical outcomes than conventional β-blocker therapy did in patients with acute MI in the modern reperfusion era. Vasodilating β-blockers could be recommended preferentially to conventional ones for acute MI patients.

Indexed as

Percutaneous Coronary InterventionAdrenergic beta-AntagonistsAgedChi-Square DistributionFemaleHeart FailureHospitalizationHumansIncidenceKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPropensity ScoreAdrenergic beta-AntagonistsVasodilator Agentsacute myocardial infarctionbeta‐blockercohort studyprognosispropensity score

Identifiers

PMID29066446
PMCPMC5721887
OpenAlexW2766553973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.