Evidence map›Paper›PMID 29066363›Full record

ArticleThe Journal of urology2018

Long-Term Renal Function Recovery following Radical Nephrectomy for Kidney Cancer: Results from a Multicenter Confirmatory Study.

Emily C Zabor, Helena Furberg, Byron Lee, Steven Campbell, Brian R Lane, R Houston Thompson, Elvis Caraballo Antonio, Sabrina L Noyes, Harras Zaid, Edgar A Jaimes and 1 more

Abstract readMulticenter Study
In one paragraph

Article in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  16. [Renal functional compensation after unilateral radical nephrectomy of renal cell carcinoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
    Article
  17. Nephron-sparing management of upper tract urothelial carcinoma.Investigative and clinical urology · 2021
    Review
  18. Review
  19. Predictors of long-term renal function after kidney surgery for patients with preoperative chronic kidney disease.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Emily C ZaborDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: zabore@mskcc.org.
Helena FurbergDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Byron LeeCenter for Urologic Oncology, Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Steven CampbellCenter for Urologic Oncology, Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Brian R LaneUrologic Oncology, Spectrum Health, Grand Rapids, Michigan.
R Houston ThompsonDepartment of Urology, Mayo Clinic, Rochester, Minnesota.
Elvis Caraballo AntonioCenter for Urologic Oncology, Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
Sabrina L NoyesUrologic Oncology, Spectrum Health, Grand Rapids, Michigan.
Harras ZaidDepartment of Urology, Mayo Clinic, Rochester, Minnesota.
Edgar A JaimesRenal Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Paul RussoUrology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Memorial Sloan Kettering Cancer Center · USCleveland Clinic · USMayo Clinic · USCorewell Health Blodgett Hospital · USSpectrum Health · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeWe sought to confirm the findings from a previous single institution study of 572 patients from Memorial Sloan Kettering Cancer Center in which we found that 49% of patients recovered to the preoperative estimated glomerular filtration rate within 2 years following radical nephrectomy for renal cell carcinoma. MATERIALS AND

methodsA multicenter retrospective study was performed in 1,928 patients using data contributed from 3 independent centers. The outcome of interest was postoperative recovery to the preoperative estimated glomerular filtration rate. Data were analyzed using cumulative incidence and competing risks regression with death from any cause treated as a competing event.

resultsThis study demonstrated that 45% of patients had recovered to the preoperative estimated glomerular filtration rate by 2 years following radical nephrectomy. Furthermore, this study confirmed that recovery of renal function differed according to preoperative renal function such that patients with a lower preoperative estimated glomerular filtration rate had an increased chance of recovery. This study also suggested that larger tumor size and female gender were significantly associated with an increased chance of renal function recovery.

conclusionsIn this multicenter retrospective study we confirmed that in the long term a large proportion of patients recover to preoperative renal function following radical nephrectomy for kidney tumors. Recovery is more likely among those with a lower preoperative estimated glomerular filtration rate.

Indexed as

Glomerular Filtration RateNephrectomyRecovery of FunctionAgedFemaleFollow-Up StudiesHumansKidneyKidney NeoplasmsMaleMiddle AgedPostoperative PeriodPreoperative PeriodRetrospective StudiesRisk FactorsSex Factorscarcinomacreatininekidneykidney function testsnephrectomyrenal cell

Identifiers

PMID29066363
PMCPMC6226274
OpenAlexW2766974582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.