Evidence map›Paper›PMID 29065631›Full record

ArticleJournal of healthcare engineering2017

Association Patterns of Ontological Features Signify Electronic Health Records in Liver Cancer.

Lawrence W C Chan, S C Cesar Wong, Choo Chiap Chiau, Tak-Ming Chan, Liang Tao, Jinghan Feng, Keith W H Chiu

Abstract read
In one paragraph

Article in Journal of healthcare engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lawrence W C ChanDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Hong Kong.ORCID 0000-0001-6451-2273
S C Cesar WongDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Choo Chiap ChiauPhilips Research China, Shanghai, China.
Tak-Ming ChanPhilips Research China, Shanghai, China.
Liang TaoPhilips Research China, Shanghai, China.ORCID 0000-0001-6233-9518
Jinghan FengPhilips Research China, Shanghai, China.
Keith W H ChiuDepartment of Diagnostic Radiology, University of Hong Kong, Pok Fu Lam, Hong Kong.ORCID 0000-0002-7930-1193

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic Health Record (EHR) system enables clinical decision support. In this study, a set of 112 abdominal computed tomography imaging examination reports, consisting of 59 cases of hepatocellular carcinoma (HCC) or liver metastases (so-called HCC group for simplicity) and 53 cases with no abnormality detected (NAD group), were collected from four hospitals in Hong Kong. We extracted terms related to liver cancer from the reports and mapped them to ontological features using Systematized Nomenclature of Medicine (SNOMED) Clinical Terms (CT). The primary predictor panel was formed by these ontological features. Association levels between every two features in the HCC and NAD groups were quantified using Pearson's correlation coefficient. The HCC group reveals a distinct association pattern that signifies liver cancer and provides clinical decision support for suspected cases, motivating the inclusion of new features to form the augmented predictor panel. Logistic regression analysis with stepwise forward procedure was applied to the primary and augmented predictor sets, respectively. The obtained model with the new features attained 84.7% sensitivity and 88.4% overall accuracy in distinguishing HCC from NAD cases, which were significantly improved when compared with that without the new features.

Indexed as

Decision Support Systems, ClinicalElectronic Health RecordsAlgorithmsCarcinoma, HepatocellularHong KongHumansLiver NeoplasmsSystematized Nomenclature of MedicineTomography, X-Ray Computed

Identifiers

PMID29065631
PMCPMC5563431

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.