Evidence map›Paper›PMID 29065563›Full record

ArticleMolecules (Basel, Switzerland)2017

Silver Nanoparticles Stabilised by Cationic Gemini Surfactants with Variable Spacer Length.

Martin Pisárčik, Josef Jampílek, Miloš Lukáč, Renáta Horáková, Ferdinand Devínsky, Marián Bukovský, Michal Kalina, Jakub Tkacz, Tomáš Opravil

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martin PisárčikDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, Bratislava SK-83232, Slovakia. pisarcik@fpharm.uniba.sk.
Josef JampílekDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava SK-83232, Slovakia. josef.jampilek@gmail.com.
Miloš LukáčDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, Bratislava SK-83232, Slovakia. lukac@fpharm.uniba.sk.
Renáta HorákováDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, Bratislava SK-83232, Slovakia. horakova@fpharm.uniba.sk.
Ferdinand DevínskyDepartment of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, Bratislava SK-83232, Slovakia. devinsky@fpharm.uniba.sk.ORCID 0000-0002-8059-9994
Marián BukovskýDepartment of Cell and Molecular Biology of Drugs, Faculty of Pharmacy, Comenius University, Bratislava SK-83232, Slovakia. bukovsky@fpharm.uniba.sk.
Michal KalinaMaterials Research Centre, Faculty of Chemistry, Brno University of Technology, CZ-61200 Brno, Czech Republic. kalina-m@fch.vut.cz.
Jakub TkaczMaterials Research Centre, Faculty of Chemistry, Brno University of Technology, CZ-61200 Brno, Czech Republic. tkacz@fch.vut.cz.ORCID 0000-0003-4586-055X
Tomáš OpravilMaterials Research Centre, Faculty of Chemistry, Brno University of Technology, CZ-61200 Brno, Czech Republic. opravil@fch.vutbr.cz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study is focused on the synthesis and investigation of the physicochemical and biological properties of silver nanoparticles stabilized with a series of cationic gemini surfactants having a polymethylene spacer of variable length. UV-VIS spectroscopy, dynamic light scattering, scanning electron microscopy and zeta potential measurements were applied to provide physicochemical characterization of the silver nanoparticles. The mean size values of the nanoparticles were found to be in the 50 to 115 nm range. From the nanoparticle size distributions and scanning electron microscopy images it results that a population of small nanoparticles with the size of several nanometers was confirmed if the nanoparticles were stabilized with gemini molecules with either a short methylene spacer (two or four -CH₂- groups) or a long spacer (12 -CH₂- groups). The average zeta potential value for silver nanoparticles stabilized with gemini molecules is roughly independent of gemini surfactant spacer length and is approx. +58 mV. An interaction model between silver nanoparticles and gemini molecules which reflects the gained experimental data, is suggested. Microbicidal activity determinations revealed that the silver nanoparticles stabilized with gemini surfactants are more efficient against Gram-negative bacteria and yeasts, which has a direct relation to the interaction mechanism of nanoparticles with the bacterial cell membrane and its structural composition.

Indexed as

Anti-Infective AgentsFungiGram-Negative BacteriaMetal NanoparticlesMicellesSilverSurface-Active AgentsAnti-Infective AgentsMicellesSilverSurface-Active Agentsgemini surfactantmicrobicidal activitynanoparticle stabilitysilver nanoparticlesurfactant spacer

Identifiers

PMID29065563
PMCPMC6151783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.