Evidence map›Paper›PMID 29065501›Full record

ReviewCells2017

Standard Assays for the Study of Autophagy in the Ex Vivo Retina.

Raquel Gómez-Sintes, Beatriz Villarejo-Zori, Ana Serrano-Puebla, Lorena Esteban-Martínez, Elena Sierra-Filardi, Ignacio Ramírez-Pardo, Natalia Rodríguez-Muela, Patricia Boya

Abstract readReview
In one paragraph

Review in Cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Fast and quantitative mitophagy assessment by flow cytometry using theFrontiers in cell and developmental biology · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Intravital imaging of mouse embryos.Science (New York, N.Y.) · 2020
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raquel Gómez-SintesDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. rgomez@cib.csic.es.
Beatriz Villarejo-ZoriDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. bvillarejo@cib.csic.es.
Ana Serrano-PueblaDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. anaserrano@cib.csic.es.
Lorena Esteban-MartínezDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. lestebanm@cnic.es.
Elena Sierra-FilardiDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. esierra@cib.csic.es.ORCID 0000-0003-4439-2037
Ignacio Ramírez-PardoDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. naxo_nx3@hotmail.com.
Natalia Rodríguez-MuelaDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. natalia2810@hotmail.com.
Patricia BoyaDepartament of Cellular and Molecular Biology, Centro de Investigaciones Biológicas, CSIC, 28040 Madrid, Spain. patricia.boya@csic.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a catabolic pathway that mediates the degradation and recycling of intracellular components, and is a key player in a variety of physiological processes in cells and tissues. Recent studies of autophagy in the eye suggest that this pathway is fundamental for the preservation of retinal homeostasis. Given its accessible location outside the brain, the retina is an ideal organ in which to study the central nervous system and a wide range of neuronal processes, from development to neurodegeneration. Here we review several methods used to assess autophagy in the retina in both physiological and pathological conditions.

Indexed as

autophagylysosomesmitophagyorganotypic culturesretina

Identifiers

PMID29065501
PMCPMC5755496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.