Evidence map›Paper›PMID 29065249›Full record

ReviewAdvanced healthcare materials2017

Fundamentals of Laser-Based Hydrogel Degradation and Applications in Cell and Tissue Engineering.

Shantanu Pradhan, Keely A Keller, John L Sperduto, John H Slater

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Engineering in vitro vascular microsystems.Microsystems & nanoengineering · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Synthetic living materials in cancer biology.Nature reviews bioengineering · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shantanu PradhanDepartment of Biomedical Engineering, University of Delaware, 150 Academy Street, 161 Colburn Lab, Newark, DE, 19716, USA.
Keely A KellerDepartment of Biomedical Engineering, University of Delaware, 150 Academy Street, 161 Colburn Lab, Newark, DE, 19716, USA.
John L SperdutoDepartment of Biomedical Engineering, University of Delaware, 150 Academy Street, 161 Colburn Lab, Newark, DE, 19716, USA.
John H SlaterDepartment of Biomedical Engineering, University of Delaware, 150 Academy Street, 161 Colburn Lab, Newark, DE, 19716, USA.ORCID http://orcid.org/0000-0002-2453-6665

Funding

A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant MicrometastasesR21CA214299 · NCI · UNIVERSITY OF DELAWARE · PI SLATER, JOHN HUNDLEY · 2017 to 2019
$588k
NCI NIH HHS R21 CA214299
6 · The paper itself

Abstract

The cell and tissue engineering fields have profited immensely through the implementation of highly structured biomaterials. The development and implementation of advanced biofabrication techniques have established new avenues for generating biomimetic scaffolds for a multitude of cell and tissue engineering applications. Among these, laser-based degradation of biomaterials is implemented to achieve user-directed features and functionalities within biomimetic scaffolds. This review offers an overview of the physical mechanisms that govern laser-material interactions and specifically, laser-hydrogel interactions. The influences of both laser and material properties on efficient, high-resolution hydrogel degradation are discussed and the current application space in cell and tissue engineering is reviewed. This review aims to acquaint readers with the capability and uses of laser-based degradation of biomaterials, so that it may be easily and widely adopted.

Indexed as

Tissue EngineeringBiocompatible MaterialsBiomimetic MaterialsCell MovementCells, ImmobilizedFibroblastsFibroinsHumansHydrogelsMesenchymal Stem CellsModels, TheoreticalTissue ScaffoldsBiocompatible MaterialsFibroinsfibroin, silkwormHydrogelsbiofabricationbiomaterialsbiomimeticscell migrationmicrofluidicsmicrophysiological systemsneuronal guidance

Identifiers

PMID29065249
PMCPMC5797692

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.