Evidence map›Paper›PMID 29065141›Full record

ArticlePloS one2017

High-performance wireless powering for peripheral nerve neuromodulation systems.

Yuji Tanabe, John S Ho, Jiayin Liu, Song-Yan Liao, Zhe Zhen, Stephanie Hsu, Chika Shuto, Zi-Yi Zhu, Andrew Ma, Christopher Vassos and 3 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Highly Miniaturized, Chronically Implanted ASIC for Electrical Nerve Stimulation.IEEE transactions on biomedical circuits and systems · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. ReStore: A wireless peripheral nerve stimulation system.Journal of neuroscience methods · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuji TanabeDepartment of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.ORCID http://orcid.org/0000-0003-4612-7771
John S HoDepartment of Electrical and Computer Engineering, National University of Singapore, Singapore 117583, Singapore.ORCID http://orcid.org/0000-0002-9458-9033
Jiayin LiuCenter for Innovation and Strategic Collaboration, St. Jude Medical, Inc., Orange County, California 92618, United States of America.
Song-Yan LiaoDepartment of Medicine, University of Hong Kong, Hong Kong, China.
Zhe ZhenDepartment of Medicine, University of Hong Kong, Hong Kong, China.
Stephanie HsuDepartment of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.
Chika ShutoCenter for Innovation and Strategic Collaboration, St. Jude Medical, Inc., Orange County, California 92618, United States of America.
Zi-Yi ZhuDepartment of Medicine, University of Hong Kong, Hong Kong, China.
Andrew MaDepartment of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.
Christopher VassosDepartment of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.
Peter ChenCenter for Innovation and Strategic Collaboration, St. Jude Medical, Inc., Orange County, California 92618, United States of America.
Hung Fat TseDepartment of Medicine, University of Hong Kong, Hong Kong, China.
Ada S Y PoonDepartment of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.

Funding

Midfield Wireless Powering and Communication System for Deeply Implanted, Minuscule SensorsR21EB020894 · NIBIB · STANFORD UNIVERSITY · PI POON, ADA SHUK YAN · 2016 to 2017
$402k
NIBIB NIH HHS R21 EB020894
6 · The paper itself

Abstract

Neuromodulation of peripheral nerves with bioelectronic devices is a promising approach for treating a wide range of disorders. Wireless powering could enable long-term operation of these devices, but achieving high performance for miniaturized and deeply placed devices remains a technological challenge. We report the miniaturized integration of a wireless powering system in soft neuromodulation device (15 mm length, 2.7 mm diameter) and demonstrate high performance (about 10%) during in vivo wireless stimulation of the vagus nerve in a porcine animal model. The increased performance is enabled by the generation of a focused and circularly polarized field that enhances efficiency and provides immunity to polarization misalignment. These performance characteristics establish the clinical potential of wireless powering for emerging therapies based on neuromodulation.

Indexed as

AnimalsElectrodesEquipment DesignFemaleMiniaturizationPeripheral NervesSwineWireless Technology

Identifiers

PMID29065141
PMCPMC5655495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.