Evidence map›Paper›PMID 29065126›Full record

SynthesisPLoS neglected tropical diseases2017

Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications.

Camila Henriques Coelho, Maurício Durigan, Diego Averaldo Guiguet Leal, Adriano de Bernardi Schneider, Regina Maura Bueno Franco, Steven M Singer

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Rodent-Borne Parasites and Human Disease: A Growing Public Health Concern.Animals : an open access journal from MDPI · 2025
    Review
  4. Article
  5. Identification of the emerging fungal pathogens in Brazilian children infected byFrontiers in cellular and infection microbiology · 2025
    Article
  6. First Characterization and Zoonotic Potential Evaluation ofTransboundary and emerging diseases · 2025
    Article
  7. Article
  8. Diagnosis ofBrazilian journal of veterinary medicine · 2024
    Article
  9. Article
  10. Burden and Epidemiology of Human IntestinalTropical medicine and infectious disease · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Life (Basel, Switzerland) · 2021
    Review
  15. Multilocus Genotyping ofPathogens (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Article
  18. Recirculation ofFrontiers in microbiology · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Camila Henriques CoelhoBiology Department, Georgetown University, Washington DC, United States of America.ORCID http://orcid.org/0000-0002-7885-9996
Maurício DuriganU.S. FDA, OARSA, CFSAN, Laurel, MD, United States of America.
Diego Averaldo Guiguet LealBasic Pathology Department, Biological Sciences Sector, Federal University of Paraná, Curitiba, Brazil.
Adriano de Bernardi SchneiderDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, NC, United States of America.
Regina Maura Bueno FrancoAnimal Biology Department, Biology Institute, University of Campinas, Campinas, Brazil.
Steven M SingerBiology Department, Georgetown University, Washington DC, United States of America.
Georgetown University · USCenter for Food Safety and Applied Nutrition · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Paraná · BRUniversity of North Carolina at Charlotte · US

Funding

The Role of Macrophages in Immune Responses to GiardiaR15AI109591 · NIAID · GEORGETOWN UNIVERSITY · PI SINGER, STEVEN M · 2014 to 2023
$1.5M
NIAID NIH HHS R15 AI109591
6 · The paper itself

Abstract

introductionGiardiasis is an intestinal infection that affects more than two hundred million people annually worldwide; it is caused by the flagellated protozoan Giardia duodenalis. In tropical countries and in low or middle-income settings, like Brazil, its prevalence can be high. There is currently no systematic review on the presence of G. duodenalis in patients, animals or water sources in Brazil.

methodsThis systematic review was performed according to recommendations established by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). As databases for our searches, we have used PubMed, Embase, Scopus and the Brazilian database SciELO using the keywords «Giardia*» and «Brazil».

resultsThis systematic review identified research studies related to G. duodenalis in water, giardiasis in animals, prevalence of giardiasis across Brazilian regions, genotyping of strains isolated in humans, and giardiasis in indigenous populations. We also propose a network of G. duodenalis transmission in Brazil based on genotypes analyses.

conclusionThis is the first time within the last twenty years that a review is being published on the occurrence of G. duodenalis in Brazil, addressing relevant issues such as prevalence, molecular epidemiology and analytical methods for parasite detection.

Indexed as

BrazilGiardiasisHumansNeglected Diseases

Identifiers

PMID29065126
PMCPMC5678545
OpenAlexW2765500807

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.