Evidence map›Paper›PMID 29064383›Full record

ReviewMarine drugs2017

Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids.

Jin Liu, Xu-Wen Li, Yue-Wei Guo

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Development in medicinal chemistryPharmaceutical patent analyst · 2024
    Review
  5. Enantioselective Total Synthesis of (+)-KB343.Journal of the American Chemical Society · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Marine sponges of the genusActa pharmaceutica Sinica. B · 2019
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jin LiuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China. ljin080@mail.ustc.edu.cn.ORCID 0000-0001-9490-0955
Xu-Wen LiState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China. xwli@simm.ac.cn.ORCID 0000-0001-7919-9726
Yue-Wei GuoState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China. ywguo@simm.ac.cn.ORCID 0000-0003-0413-2070
Chinese Academy of Sciences · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. This review focused on the guanidine alkaloids derived from marine sources and discussed the recent progress on their isolation, synthesis and biological activities, covering the literature from the year 2010 to the present.

Indexed as

AlkaloidsAnimalsAnti-Infective AgentsAntineoplastic AgentsAquatic OrganismsBiological ProductsGuanidinesHumansInhibitory Concentration 50Oceans and SeasStructure-Activity RelationshipAlkaloidsAnti-Infective AgentsAntineoplastic AgentsBiological ProductsGuanidinesascidianbiological activitymarine guanidine alkaloidsmolluskspongetotal synthesis

Identifiers

PMID29064383
PMCPMC5666430
OpenAlexW2766965694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.