Evidence map›Paper›PMID 29064008›Full record

ArticleEuropean journal of epidemiology2018

Paediatric population neuroimaging and the Generation R Study: the second wave.

Tonya White, Ryan L Muetzel, Hanan El Marroun, Laura M E Blanken, Philip Jansen, Koen Bolhuis, Desana Kocevska, Sabine E Mous, Rosa Mulder, Vincent W V Jaddoe and 3 more

Abstract read
In one paragraph

Article in European journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
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  19. It Takes Three: Parental Hostility, Brain Morphology, and Child Externalizing Problems in a Parent-Offspring Neuroimaging Trio Design.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tonya WhiteDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands. t.white@erasmusmc.nl.ORCID 0000-0003-0271-1896
Ryan L MuetzelDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Hanan El MarrounDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Laura M E BlankenDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Philip JansenDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Koen BolhuisDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Desana KocevskaDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Sabine E MousDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Rosa MulderDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Vincent W V JaddoeThe Generation R Study Group, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Aad van der LugtDepartment of Radiology, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Frank C VerhulstDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.
Henning TiemeierDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Kp-2869, Postbus 2060, 3000 CB, Rotterdam, The Netherlands.

Funding

ZonMw 91211021
6 · The paper itself

Abstract

Paediatric population neuroimaging is an emerging field that falls at the intersection between developmental neuroscience and epidemiology. A key feature of population neuroimaging studies involves large-scale recruitment that is representative of the general population. One successful approach for population neuroimaging is to embed neuroimaging studies within large epidemiological cohorts. The Generation R Study is a large, prospective population-based birth-cohort in which nearly 10,000 pregnant mothers were recruited between 2002 and 2006 with repeated measurements in the children and their parents over time. Magnetic resonance imaging was included in 2009 with the scanning of 1070 6-to-9-year-old children. The second neuroimaging wave was initiated in April 2013 with a total of 4245 visiting the MRI suite and 4087 9-to-11-year-old children being scanned. The sequences included high-resolution structural MRI, 35-direction diffusion weighted imaging, and a 6 min and 2 s resting-state functional MRI scan. The goal of this paper is to provide an overview of the imaging protocol and the overlap between the neuroimaging data and metadata. We conclude by providing a brief overview of results from our first wave of neuroimaging, which highlights a diverse array of questions that can be addressed by merging the fields of developmental neuroscience and epidemiology.

Indexed as

BrainChildFemaleHumansMagnetic Resonance ImagingMaleNetherlandsNeuroimagingNeurosciencesPediatricsPopulation SurveillanceProspective StudiesAutism spectrum disordersBehaviourBrain developmentCognitive developmentDevelopmental neuroscienceNeurodevelopmentNeuroimaging

Identifiers

PMID29064008
PMCPMC5803295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.