Evidence map›Paper›PMID 29063831›Full record

ArticleeLife2017

Theta-burst microstimulation in the human entorhinal area improves memory specificity.

Ali S Titiz, Michael R H Hill, Emily A Mankin, Zahra M Aghajan, Dawn Eliashiv, Natalia Tchemodanov, Uri Maoz, John Stern, Michelle E Tran, Peter Schuette and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 126 citations in OpenAlex.

  1. Review
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  7. Reading specific memories from human neurons before and after sleep.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
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  10. Exploring individual differences in amygdala-mediated memory modulation.Cognitive, affective & behavioral neuroscience · 2025
    Article
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  18. Review
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ali S TitizDepartment of Neurosurgery, University of California, Los Angeles, United States.
Michael R H HillDepartment of Neurosurgery, University of California, Los Angeles, United States.
Emily A MankinDepartment of Neurosurgery, University of California, Los Angeles, United States.ORCID 0000-0003-2163-913X
Zahra M AghajanDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, United States.ORCID 0000-0003-4245-3975
Dawn EliashivDepartment of Neurology, University of California, Los Angeles, United States.
Natalia TchemodanovDepartment of Neurosurgery, University of California, Los Angeles, United States.
Uri MaozDepartment of Neurosurgery, University of California, Los Angeles, United States.
John SternDepartment of Neurology, University of California, Los Angeles, United States.
Michelle E TranDepartment of Neurosurgery, University of California, Los Angeles, United States.
Peter SchuetteDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, United States.
Eric BehnkeDepartment of Neurosurgery, University of California, Los Angeles, United States.
Nanthia A SuthanaDepartment of Neurosurgery, University of California, Los Angeles, United States.
Itzhak FriedDepartment of Neurosurgery, University of California, Los Angeles, United States.ORCID 0000-0002-5962-2678
University of California, Los Angeles · USCalifornia Institute of Technology · US

Funding

Mechanisms of Memory Enhancement by Deep Brain Stimulation in HumansR01NS084017 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FRIED, ITZHAK · 2013 to 2022
$4.7M
Neurostimulation and Recording of Real World Spatial Navigation in HumansU01NS103802 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUTHANA, NANTHIA A · 2017 to 2019
$3.4M
6 · The paper itself

Abstract

The hippocampus is critical for episodic memory, and synaptic changes induced by long-term potentiation (LTP) are thought to underlie memory formation. In rodents, hippocampal LTP may be induced through electrical stimulation of the perforant path. To test whether similar techniques could improve episodic memory in humans, we implemented a microstimulation technique that allowed delivery of low-current electrical stimulation via 100

Indexed as

Long-Term PotentiationMemoryTheta RhythmElectric StimulationEntorhinal CortexHumansMicroelectrodesdeep brain stimulationepisodic memoryhippocampushumanhuman biologymedial temporal lobemedicinemicrostimulationneuroscience

Identifiers

PMID29063831
PMCPMC5655155
OpenAlexW2765293442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.