Evidence map›Paper›PMID 29063828›Full record

Trial reportParasite (Paris, France)2017

Assessment of the insecticidal activity of afoxolaner against Aedes aegypti in dogs treated with NexGard

Julian Liebenberg, Josephus Fourie, Wilfried Lebon, Diane Larsen, Lenaïg Halos, Frédéric Beugnet

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Parasite (Paris, France), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Safeguarding Canadian pets and humans: A call to strengthen regulations for importing companion animals.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2026
    Review
  2. Article
  3. Fluralaner (BravectoParasites & vectors · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Insecticidal efficacy of afoxolaner againstCurrent research in parasitology & vector-borne diseases · 2021
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Julian LiebenbergClinvet International (Pty) Ltd, PO Box 11186, 9321 Universitas, South Africa.
Josephus FourieClinvet International (Pty) Ltd, PO Box 11186, 9321 Universitas, South Africa.
Wilfried LebonBoehringer Ingelheim Animal Health, 29 avenue Tony Garnier, 69007 Lyon, France.
Diane LarsenBoehringer Ingelheim Animal Health, 29 avenue Tony Garnier, 69007 Lyon, France.
Lenaïg HalosBoehringer Ingelheim Animal Health, 29 avenue Tony Garnier, 69007 Lyon, France.
Frédéric BeugnetBoehringer Ingelheim Animal Health, 29 avenue Tony Garnier, 69007 Lyon, France.
Boehringer Ingelheim (France) · FRClinvet · ZADépartement Santé Animale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twelve healthy dogs were studied in this parallel group, blinded, randomised, and negative controlled efficacy study. On Day -1, the 12 dogs included were ranked within sex in descending order of individual pre-treatment (Day -5) fed mosquito counts and randomly allocated by blocks of two dogs to the untreated control group or the afoxolaner-treated group. NexGard

Indexed as

AedesInsecticidesInsect VectorsIsoxazolesNaphthalenesAdministration, OralAnalysis of VarianceAnimalsBody WeightDog DiseasesDogsEctoparasitic InfestationsFemaleMaleafoxolanerInsecticidesIsoxazolesNaphthalenes

Identifiers

PMID29063828
PMCPMC5654328
OpenAlexW2766509050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.