Evidence map›Paper›PMID 29063662›Full record

ArticleThe breast journal2018

Breast density in multiethnic women presenting for screening mammography.

Bridget A Oppong, Chiranjeev Dash, Suzanne O'Neill, Yinan Li, Kepher Makambi, Edward Pien, Erini Makariou, Tesha Coleman, Lucile L Adams-Campbell

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The breast journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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  10. Impact of BMI on Prevalence of Dense Breasts by Race and Ethnicity.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  11. Body Mass Index and Mammographic Density in a Multiracial and Multiethnic Population-Based Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  12. Article
  13. Breast Density Awareness and Knowledge in a Mammography Screening Cohort of Predominantly Hispanic Women: Does Breast Density Notification Matter?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
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  15. Breast Cancer Population Attributable Risk Proportions Associated with Body Mass Index and Breast Density by Race/Ethnicity and Menopausal Status.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bridget A OppongDepartment of Surgery, Georgetown University Hospital, Washington, DC, USA.ORCID 0000-0002-1696-4491
Chiranjeev DashGeorgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Suzanne O'NeillGeorgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Yinan LiDepartment of Biostatics, Bioinformatics, and Biomathematics, Georgetown University Hospital, Washington, DC, USA.
Kepher MakambiDepartment of Biostatics, Bioinformatics, and Biomathematics, Georgetown University Hospital, Washington, DC, USA.
Edward PienDepartment of Radiology, Georgetown University Hospital, Washington, DC, USA.
Erini MakariouDepartment of Radiology, Georgetown University Hospital, Washington, DC, USA.
Tesha ColemanCapital Breast Care Center, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Lucile L Adams-CampbellGeorgetown University Lombardi Comprehensive Cancer Center, Washington, DC, USA.ORCID 0000-0002-3444-3884
Georgetown University · USGeorgetown University Medical Center · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
Molecular Epidemiology of Oxidative Stress and Related Cancers in Black WomenK07CA197112 · NCI · GEORGETOWN UNIVERSITY · PI DASH, CHIRANJEEV · 2016 to 2020
$655k
NCI NIH HHS K07 CA197112NCI NIH HHS P30 CA051008
6 · The paper itself

Abstract

Data on ethnic variations in breast density are limited and often not inclusive of underrepresented minorities. As breast density is associated with elevated breast cancer risk, investigating racial and ethnic difference may elucidate the observed differences in breast cancer risk among different populations. We reviewed breast density from initial screening of women from the Capital Breast Care Center and Georgetown University Hospital from 2010 to 2014. Patient demographics including race, age at screening, education, menopausal status, and body mass index were abstracted. We recorded the BI-RADS density categories: (1) "fatty," (2) "scattered fibroglandular densities," (3) "heterogeneously dense," and (4) "extremely dense." Multivariable unconditional logistic regression was used to identify predictors of breast density. Density categorization was recorded for 2146 women over the 5-year period, comprising Blacks (n = 940), Hispanics (n = 893), and Whites (n = 314). Analysis of subject characteristics by breast density showed that high category is observed in younger, Hispanic, nulliparous, premenopausal, and nonobese women (t-test or chi-square test, P-values <.0001). Obese women are 70% less likely to have high density. Being Hispanic, premenopausal, and nonobese were predictive of high density on logistic regression. In this analysis of density distribution in a diverse sample, Hispanic women have the highest breast density, followed by Blacks and Whites. Unique in our findings is women who identify as Hispanic have the highest breast density and lower rates of obesity. Further investigation of the impact of obesity on breast density, especially in the understudied Hispanic group is needed.

Indexed as

AdultBlack or African AmericanBody Mass IndexBreast DensityBreast NeoplasmsFemaleHispanic or LatinoHumansLogistic ModelsMammographyMiddle AgedWhite PeopleBI-RADSBlacksHispanicsmammographic density

Identifiers

PMID29063662
PMCPMC5916740
OpenAlexW2766522507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.