Evidence map›Paper›PMID 29063613›Full record

ArticleAlcoholism, clinical and experimental research2018

Interactive Effects of Maternal Alcohol Problems and Parental Separation on Timing of Daughter's First Drink.

Mary Waldron, Nicole K Watkins, Kathleen K Bucholz, Pamela A F Madden, Andrew C Heath

Open access · greenAbstract readTwin Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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  7. Heterogeneity in effects of parent-child separation on young-adult substance use disorder.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mary WaldronDepartment of Counseling & Educational Psychology, Indiana University, Bloomington, Indiana.ORCID 0000-0002-7486-5897
Nicole K WatkinsDepartment of Counseling & Educational Psychology, Indiana University, Bloomington, Indiana.
Kathleen K BucholzMidwest Alcoholism Research Center and Family Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0003-3794-0736
Pamela A F MaddenMidwest Alcoholism Research Center and Family Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Andrew C HeathMidwest Alcoholism Research Center and Family Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USIndiana University Bloomington · US

Funding

PILOT--GENETIC EPIDEMIOLOGY OF ALCOHOL AND TOBACCO CONSUMPTION IN CHINESE SAMPLEP50AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI SHER, KENNETH JAMES · 1999 to 2008
$12.6M
Resource CoreP60AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI MADDEN, PAMELA ANN · 2009 to 2013
$8.8M
ALCOHOLISM: GENETIC EPIDEMIOLOGIC TWIN STUDYR01AA009022 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1994 to 2004
$3.3M
ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7R01AA017915 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2009 to 2013
$3.2M
GxE in Early Childhood: Twin MothersR01HD049024 · NICHD · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2005 to 2009
$2.9M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
NIAAA NIH HHS K05 AA017688NIAAA NIH HHS P50 AA011998NIAAA NIH HHS P60 AA011998NIAAA NIH HHS R01 AA009022NIAAA NIH HHS R01 AA017915NICHD NIH HHS R01 HD049024
6 · The paper itself

Abstract

backgroundFew studies examine risk to offspring who experience both parental alcohol problems and parental separation and still fewer consider gender of the affected parent. We examined interactive effects of maternal versus paternal alcohol problems and parental separation on timing of first alcoholic drink in daughters.

methodsData were drawn from a sample of 3,539 European (or other) ancestry (EA) and 611 African ancestry (AA) female twins born between 1975 and 1985, median age 15 at first assessment. Cox proportional hazards regression models were estimated predicting age at first full drink from parental history of alcohol problems (mother only, father only, or both parents), parental separation during childhood, and the interaction of parental alcohol problems and parental separation. Cox models were estimated without and with adjustment for correlated risk factors, separately for EA and AA twins.

resultsFor both EA and AA twins, a significant interaction between parental separation and mother-only alcohol problems was observed, suggesting reduced risk of drinking associated with mother-only alcohol problems in separated versus intact families.

conclusionsFindings highlight parental separation as an important moderator of risk to children of mothers who have a history of problem drinking, with interactive effects observed consistently across racial group. To identify underlying processes, additional research is needed with more detailed characterization of separated families where mother only has a history of alcohol problems.

Indexed as

AdolescentAlcoholismCohort StudiesDivorceFemaleHumansMaternal BehaviorNuclear FamilyParentsTime FactorsUnderage DrinkingYoung AdultOnset of Alcohol UseParental Alcohol ProblemsParental Separation or Divorce

Identifiers

PMID29063613
PMCPMC5750092
OpenAlexW2765375786

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.