Evidence map›Paper›PMID 29063505›Full record

ArticleBrain imaging and behavior2018

Control beliefs are associated with preserved memory function in the face of low hippocampal volume among diverse older adults.

Laura B Zahodne, Nicole Schupf, Adam M Brickman

Open access · greenAbstract read
In one paragraph

Article in Brain imaging and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Psychosocial Protective Factors in Cognitive Aging: A Targeted Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Laura B ZahodneDepartment of Psychology, University of Michigan, 530 Church Street, Ann Arbor, MI, 48104, USA. lzahodne@umich.edu.
Nicole SchupfDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Adam M BrickmanGertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Columbia University · USUniversity of Michigan–Ann Arbor · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
VASCULAR FACTORS AND MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASEP01AG007232 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI LUCHSINGER, JOSE ALEJANDRO · 1989 to 2008
$21.7M
Epidemiology of Biomarkers of Risk and Progression in LOADR01AG037212 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, SCHUPF, NICOLE · 2010 to 2015
$10.1M
Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's DiseaseRF1AG054023 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2016 to 2018
$8.9M
Resilience Mechanisms Underlying Racial/Ethnic Disparities in Alzheimer’s DiseaseR01AG054520 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M, ZAHODNE, LAURA B · 2017 to 2021
$5.8M
COGNITIVE TEST PERFORMANCE OF AFRICAN AMERICAN ELDERSR01AG016206 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANLY, JENNIFER JAIE · 1999 to 2008
$2.9M
White matter hyperintensities in Aging and DementiaR01AG034189 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M · 2010 to 2014
$2.0M
White Matter Hyperintentisities in Aging and DementiaR56AG034189 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M · 2016 to 2016
$793k
Psychosocial Protective Factors in Cognitive and Brain AgingR00AG047963 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZAHODNE, LAURA B · 2016 to 2018
$746k
National Center for Advancing Translational Sciences TR001873National Institute on Aging AG016206National Institute on Aging AG034189National Institute on Aging AG037212National Institute on Aging AG047963National Institute on Aging AG054023National Institute on Aging AG07232NCATS NIH HHS UL1 TR001873NIA NIH HHS P01 AG007232NIA NIH HHS R00 AG047963NIA NIH HHS R01 AG016206NIA NIH HHS R01 AG034189NIA NIH HHS R01 AG037212NIA NIH HHS R01 AG054520NIA NIH HHS R56 AG034189NIA NIH HHS RF1 AG054023
6 · The paper itself

Abstract

Growing evidence supports a link between locus of control and memory in older adults. Control beliefs may directly predict larger hippocampal volume (i.e., brain maintenance). Alternatively, control beliefs may be associated with smaller hippocampal volume at any given level of memory (i.e., cognitive reserve). Multivariable regression analyses examined associations between verbal episodic memory, locus of control and hippocampal volume among 236 non-demented older adults in the community-based Washington Heights-Inwood Columbia Aging Project. Control beliefs were negatively associated with hippocampal volume when controlling for memory performance, indicating that individuals with stronger control beliefs were able to maintain memory function in the face of lower hippocampal volume. Subsequent exploratory models stratified by race/ethnicity indicated that this association was more prominent among racial/ethnic minorities (particularly Caribbean Hispanic older adults) than among non-Hispanic White older adults. Control beliefs were not associated with hippocampal volume before memory was taken into account. Results are consistent with the view that control beliefs facilitate the maintenance of memory function despite hippocampal volume loss. Results are not consistent with the view that locus of control contributes to brain maintenance. Culturally-appropriate interventions are needed to test whether strengthening control beliefs provides cognitive resistance to neuropathology.

Indexed as

Cognitive ReserveInternal-External ControlMagnetic Resonance ImagingMemory, EpisodicAgedCognitive AgingCross-Sectional StudiesCultureEthnicityFemaleHippocampusHumansImage Processing, Computer-AssistedLongitudinal StudiesMaleModels, NeurologicalBrain maintenanceCognitive reserveEpisodic memoryMRI

Identifiers

PMID29063505
PMCPMC5912994
OpenAlexW2765096244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.