Evidence map›Paper›PMID 29063451›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2018

Diabetic polyneuropathy, deep white matter lesions, and carotid atherosclerosis: is there any association?

Sevgi Ferik, Hayat Güven, Mehlika Panpallı Ateş, Işık Conkbayır, Selçuk Çomoğlu, Bülent Güven

Abstract read
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sevgi FerikDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Neurology, University of Health Sciences, Çiğdem mah. 1550/1 cad. 23/1 Çankaya, 06530, Ankara, Turkey.
Hayat GüvenDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Neurology, University of Health Sciences, Çiğdem mah. 1550/1 cad. 23/1 Çankaya, 06530, Ankara, Turkey. hayatguven@gmail.com.ORCID http://orcid.org/0000-0002-9135-639X
Mehlika Panpallı AteşDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Neurology, University of Health Sciences, Çiğdem mah. 1550/1 cad. 23/1 Çankaya, 06530, Ankara, Turkey.
Işık ConkbayırDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Radiology, University of Health Sciences, Ankara, Turkey.
Selçuk ÇomoğluDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Neurology, University of Health Sciences, Çiğdem mah. 1550/1 cad. 23/1 Çankaya, 06530, Ankara, Turkey.
Bülent GüvenDışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Neurology, University of Health Sciences, Çiğdem mah. 1550/1 cad. 23/1 Çankaya, 06530, Ankara, Turkey.
Sağlık Bilimleri Üniversitesi · TRÇankaya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The morphologic and functional damages of diabetes mellitus (DM) on microcirculation can play a role in the pathogenesis of both polyneuropathy and cerebral white matter lesions. The aim of this study is to investigate the relation between polyneuropathy and cerebral deep white matter lesions (DWMLs) and carotid atherosclerosis in patients with type 2 DM. Sixty-six patients with type 2 DM without any disorder that may cause polyneuropathy, and vascular risk factors except for DM and hyperlipidemia were included in the study. DWMLs and carotid atherosclerosis were investigated in patients with and without polyneuropathy. Forty patients (60.6%) had diabetic sensorimotor polyneuropathy. DWMLs were more frequent in patients with polyneuropathy compared to patients without polyneuropathy (p = 0.003). Logistic regression analysis confirmed association between polyneuropathy and DWMLs after adjusted for age (p = 0.013), duration of DM (p = 0.007), and both age and duration of DM (p = 0.016). No statistically significant difference was found between patients with and without polyneuropathy for carotid atherosclerosis. Among patients with polyneuropathy, those having DWMLs had higher mean age (p = 0.003) and longer symptom duration (p = 0.020) compared to patients without DWMLs. No association was found between DWMLs and carotid atherosclerosis. Polyneuropathy and cerebral DWMLs in type 2 DM patients may share common pathogenesis; presence and duration of polyneuropathy symptoms may predict ischemic white matter damage independent of carotid atherosclerosis.

Indexed as

BrainCarotid Artery DiseasesDiabetes Mellitus, Type 2Diabetic NeuropathiesElectromyographyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesUltrasonography, DopplerWhite MatterCarotid atherosclerosisDeep white matter lesionsDiabetic polyneuropathyType 2 diabetes mellitus

Identifiers

PMID29063451
OpenAlexW2765440062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.