Evidence map›Paper›PMID 29063274›Full record

ReviewHandbook of experimental pharmacology2018

Conserved Oligomeric Golgi and Neuronal Vesicular Trafficking.

Leslie K Climer, Rachel D Hendrix, Vladimir V Lupashin

Abstract readReview
In one paragraph

Review in Handbook of experimental pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  6. Article
  7. Article
  8. Golgi inCOGnito: From vesicle tethering to human disease.Biochimica et biophysica acta. General subjects · 2020
    Review
  9. Review
  10. Models of Intracellular Transport: Pros and Cons.Frontiers in cell and developmental biology · 2019
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leslie K ClimerCollege of Medicine, Physiology and Biophysics, UAMS, Little Rock, AR, USA.
Rachel D HendrixCollege of Medicine, Neurobiology and Developmental Sciences, UAMS, Little Rock, AR, USA.
Vladimir V LupashinCollege of Medicine, Physiology and Biophysics, UAMS, Little Rock, AR, USA. vvlupashin@uams.edu.

Funding

Characterization of mammalian COG complex-interacting intra-Golgi trafficking macR01GM083144 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI VLADIMIR V LUPASHIN · 2008 to 2026
$6.5M
Super-Res Holographic Microscopy to Advance Research on Golgi Apparatus FunctionU54GM105814 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI BROOKER, GARY, LUPASHIN, VLADIMIR V · 2013 to 2017
$2.1M
NIGMS NIH HHS R01 GM083144NIGMS NIH HHS U54 GM105814
6 · The paper itself

Abstract

The conserved oligomeric Golgi (COG) complex is an evolutionary conserved multi-subunit vesicle tethering complex essential for the majority of Golgi apparatus functions: protein and lipid glycosylation and protein sorting. COG is present in neuronal cells, but the repertoire of COG function in different Golgi-like compartments is an enigma. Defects in COG subunits cause alteration of Golgi morphology, protein trafficking, and glycosylation resulting in human congenital disorders of glycosylation (CDG) type II. In this review we summarize and critically analyze recent advances in the function of Golgi and Golgi-like compartments in neuronal cells and functions and dysfunctions of the COG complex and its partner proteins.

Indexed as

Adaptor Proteins, Vesicular TransportAnimalsGlycosylationGolgi ApparatusHumansNeuronsProtein TransportAdaptor Proteins, Vesicular TransportCOG1 protein, humanCOG2 protein, humanCOGConserved oligomeric GolgiGlycosylationGolgi outpostGolgi satellite

Identifiers

PMID29063274
PMCPMC6091216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.