ArticleEuropean radiology2018
Dual-layer DECT for multiphasic hepatic CT with 50 percent iodine load: a matched-pair comparison with a 120 kVp protocol.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Dual-energy CT applications on liver imaging: what radiologists and radiographers should know? A systematic review.Abdominal radiology (New York) · 2024Pooled it
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Clinical and experimental nephrology · 2020Guideline
- Renal protection CT protocol using low-dose and low-concentration iodine contrast medium in at-risk patients of HCC and with chronic kidney disease: a randomized controlled non-inferiority trial.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Trial
- Dual-layer spectral detector CT for improved assessment of right adrenal vein in patients with primary aldosteronism.Abdominal radiology (New York) · 2026Article
- Optimizing computed tomography enterography with virtual monoenergetic imaging of second-generation dual-layer spectral CT in inflammatory bowel disease.Quantitative imaging in medicine and surgery · 2025Article
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Image Quality and Lesion Detectability with Low-Monoenergetic Imaging: A Study of Low-Concentration Iodine Contrast in Hepatic Multiphase CT for Chronic Liver Disease.Tomography (Ann Arbor, Mich.) · 2025Article
- Contrast Volume Reduction in Oncologic Body Imaging Using Dual-Energy CT: A Comparison with Single-Energy CT.Diagnostics (Basel, Switzerland) · 2025Article
- Research Progress of Dual-energy CT in Diagnosis and Evaluation of Curative Effect of Liver Cancer: A ReviewCurrent medical imaging · 2025Review
- Photon-counting CT for pulmonary embolisms-when radiologists don't have to choose between image quality or motion artifacts.European radiology · 2024Article
- Dual-Energy CT as a Well-Established CT Modality to Reduce Contrast Media Amount: A Systematic Review from the Computed Tomography Subspecialty Section of the Italian Society of Radiology.Journal of clinical medicine · 2024Review
- Clinical Feasibility of Dual-Layer CT With Virtual Monochromatic Image for Preoperative Staging in Patients With Breast Cancer: A Comparison With Breast MRI.Korean journal of radiology · 2024Article
- Low KeV virtual monoenergetic images for detecting low dose iodine- or alternative Gd-based IV contrast agents.Heliyon · 2024Article
- An adult and pediatric size-based contrast administration reduction phantom study for single and dual-energy CT through preservation of contrast-to-noise ratio.Journal of applied clinical medical physics · 2024Article
- Deep learning-based iodine contrast-augmenting algorithm for low-contrast-dose liver CT to assess hypovascular hepatic metastasis.Abdominal radiology (New York) · 2023Article
- Advances for Pulmonary Functional Imaging: Dual-Energy Computed Tomography for Pulmonary Functional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Dual-energy CT: minimal essentials for radiologists.Japanese journal of radiology · 2022Review
- Liver fibrosis assessment with multiphasic dual-energy CT: diagnostic performance of iodine uptake parameters.European radiology · 2021Article
- Advanced CT techniques for assessing hepatocellular carcinoma.La Radiologia medica · 2021Review
- Virtual Monochromatic Image Quality from Dual-Layer Dual-Energy Computed Tomography for Detecting Brain Tumors.Korean journal of radiology · 2021Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the image quality and lesion conspicuity of virtual-monochromatic-imaging (VMI) with dual-layer DECT (DL-DECT) for reduced-iodine-load multiphasic-hepatic CT.
methodsForty-five adults with renal dysfunction who had undergone hepatic DL-DECT with 300-mgI/kg were included. VMI (40-70-keV, DL-DECT-VMI) was generated at each enhancement phase. As controls, 45 matched patients undergoing standard 120-kVp protocol (120-kVp, 600-mgI/kg, and iterative reconstruction) were included. We compared the size-specific dose estimate (SSDE), image noise, CT attenuation, and contrast-to-noise ratio (CNR) between protocols. Two radiologists scored the image quality and lesion conspicuity.
resultsSSDE was significantly lower in DL-DECT group (p < 0.01). Image noise of DL-DECT-VMI was almost constant at each keV (differences of ≤15%) and equivalent to or lower than of 120-kVp. As the energy decreased, CT attenuation and CNR gradually increased; the values of 55-60 keV images were almost equivalent to those of standard 120-kVp. The highest scores for overall quality and lesion conspicuity were assigned at 40-keV followed by 45 to 55-keV, all of which were similar to or better than of 120-kVp.
conclusionsFor multiphasic-hepatic CT with 50% iodine-load, DL-DECT-VMI at 40- to 55-keV provides equivalent or better image quality and lesion conspicuity without increasing radiation dose compared with standard 120-kVp protocol. KEY POINTS: • 40-55-keV yields optimal image quality for half-iodine-load multiphasic-hepatic CT with DL-DECT. • DL-DECT protocol decreases radiation exposure compared with 120-kVp scans with iterative reconstruction. • 40-keV images maximise conspicuity of hepatocellular carcinoma especially at hepatic-arterial phase.
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